PEUTZ syndrome

Surgical paper II

PEUTZ syndrome

A 14-Year Case Study of Three Surgical Interventions Due to Complications

 

Introduction

Peutz-Jeghers syndrome, colloquially referred to as "Melanin Spot-Multiple Gastrointestinal Polyps Syndrome" in China, was initially described by the Dutch physician Jan Peutz in 1921. The syndrome was later dubbed "Peutz-Jeghers" in 1949 after British researchers Jeghers and colleagues compiled a collection of 22 cases. Though relatively rare, the condition has garnered increasing attention, as evidenced by sporadic case reports[^1][^2] and approximately 100 reported cases within China. Nevertheless, the coverage of this disorder in academic textbooks remains scant[^3][^4].

Classified as a congenital disorder, Peutz-Jeghers syndrome is thought to arise from a developmental anomaly and belongs to the family of hamartomas. It frequently manifests with familial patterns and is characterized by distinctive dark pigmentation on the lips and fingers, as well as the presence of multiple gastrointestinal polyps. Due to its severe complications and the challenges associated with achieving a complete cure, the condition often necessitates multiple surgical interventions and poses long-term health concerns. Given its potential for delayed onset and a variety of symptomatic presentations, clinical attention to its management is of paramount importance.

In our medical facility, we managed a patient who underwent three surgical interventions over a span of 14 years. The first two surgeries were necessitated by small intestinal polyps that led to complications such as intestinal entrapment and necrosis. The third surgical procedure was an emergency intervention to alleviate a blockage in both the biliary and digestive tracts. This obstruction was caused by sizable polyps located in the descending portion of the duodenum and required immediate diversionary tactics to preserve the patient's life.

Medical History and Presentation

The patient, a 38-year-old healthcare worker, was initially admitted to our hospital on September 25, 1979, under inpatient number 3702. His medical journey began at the age of 5 when he contracted measles. Following his recovery, his parents observed persistent brown-black pigmentation on his lips and toes, which gradually intensified in both size and hue over the years. The patient also frequently experienced episodes of intermittent abdominal pain, diarrhea, and rectal bleeding, which were generally mitigated through anti-inflammatory and antiparasitic treatments.

In 1965, at the age of 24, the patient underwent his first surgical procedure at our facility for an intestinal obstruction. During the operation, multiple small intestinal polyps were discovered, along with complications of jejuno-jejunal intussusception and intestinal necrosis. Consequently, 100 cm of the jejunum was resected, and an additional ten polyps, each larger than the tip of a finger, were excised from three different locations in the small intestine. Despite these measures, numerous smaller polyps remained in situ. Postoperatively, the patient made an uneventful recovery and was duly discharged. Intermittent abdominal pain persisted but often resolved without intervention.

In 1968, a recurrence of intestinal intussusception led to a second surgical procedure. A further 60 cm of the ileum was resected, revealing an increased number and size of small intestinal polyps compared to the first operation. No palpable polyps were found in the stomach or colon at that time. Over the ensuing decade, the patient experienced three episodes of gastrointestinal bleeding, each accompanied by intermittent melena, which responded to conventional hemostatic treatments. Despite occasional bouts of abdominal pain and diarrhea, the patient reported leading a generally normal life and work routine.

In 1978, a barium meal X-ray indicated the presence of numerous polyps throughout the gastrointestinal tract. Recently, the patient began experiencing progressive jaundice, accompanied by symptoms of dyspepsia, reduced appetite, and general fatigue. Liver function tests conducted at another facility revealed a jaundice index of 25 units, positive urine bilirubin, ALT levels at 57.5 units, and alkaline phosphatase at 50 units. Four days prior to the most recent hospital admission, the patient suffered from episodes of acute upper abdominal pain, frequent vomiting, and epigastric fullness, leading to his readmission for suspected high-level intestinal obstruction.

Physical Examination and Laboratory Findings

Physical Examination:

The patient presented with dehydration, emaciation, and jaundice. Upon abdominal palpation, a water splash sign was detected, indicative of gastric stasis. Tenderness and fullness were noted in the epigastrium, specifically to the right of the xiphoid process. A relatively fixed, fleshy mass was palpable, along with hepatomegaly—liver extended 1.5 cm below the costal margin, exhibiting a blunt edge and medium texture. The lower abdomen was soft to the touch, revealing multiple movable, fleshy nodules of varying sizes. Bowel sounds were hyperactive, and no signs of ascites were found.

Dermatological Findings:

Brown-black, non-elevated, non-blanching round and oval spots were scattered around the mouth, gums, cheek mucosa, as well as the fingers and toes. In total, approximately ten such spots were observed. Additionally, a general deepening of pigmentation resembling cyanosis was noted on the lips and gums.

Laboratory Investigations:

Serum bilirubin levels were at 2.2 mg%, and a direct biphasic reaction was observed in the Vandenberg test. Hemoglobin levels measured at 10.5 gm, and the red blood cell count was 3.75 million/mm*.

Preoperative Diagnosis:

The patient was diagnosed with Peutz-Jeghers syndrome, complicated by high-level intestinal obstruction and biliary obstruction.

Surgical Interventions and Pathological Findings

Third Laparotomy

Upon admission, a third laparotomy revealed a substantially swollen descending part of the duodenum, filled with a sizeable mass. The common bile duct was notably thickened, measuring up to 3 cm in diameter. Both the liver and spleen displayed slight enlargement, while the pancreas appeared normal. Multiple fleshy nodules were palpable throughout the entire gastrointestinal tract, from the stomach to the colon. Several superficial intussusceptions were observed in the small intestine, all of which self-reverted. There was minor intestinal adhesion and numerous repair and anastomotic scars on the small intestine, with no signs of stenosis. Peritoneal yellowing was evident, but no ascites were present.

Upon incising the duodenum, a massive polyp centered around the papilla, measuring 6x5x4 cm, was discovered. This polyp, complete with ulceration, filled the intestinal lumen and had a broad base. An exploratory incision of the common bile duct revealed no stones but confirmed blockage at its duodenal outlet. A small-sized biliary dilator was successfully employed to clear the obstruction, effectively relieving obstructions in both the biliary and gastrointestinal tracts. Given the severity of the patient's condition and the suspected malignant transformation, a decision was made to perform a diversionary procedure. A biopsy was taken for pathological evaluation, and the duodenum was repaired. Anastomoses were created between the gallbladder and proximal jejunum, as well as between the stomach and distal jejunum. A "T-tube" was placed for external bile drainage, and intra-abdominal drainage was established. Other polyps causing no obstruction were left untreated.

Pathological Report

The biopsy confirmed the polyp to be benign, consistent with Peutz-Jeghers syndrome (Pathology No. 5155).

Postoperative Course

The patient made a fair postoperative recovery, with timely passage of flatus, resumption of oral intake, and rapid resolution of jaundice. On the 11th postoperative day, external duodenal atrophy and pancreatic fluid digestion were noted, initially managed by drainage and later by occlusion. The "T-tube" was removed on the 26th postoperative day, following which the external fistula healed spontaneously. After a 34-day hospital stay, the patient was discharged in good condition, with a jaundice index of 8 units and normal digestive function.

Family History

Upon retrospective examination of the patient's familial medical history, no similar conditions were reported in either parent. The patient has four children, one of whom—a 10-year-old boy—exhibited dark spots on his lips, hands, and feet at age 5, mirroring the patient's symptoms. The boy also has a history of occasional abdominal pain and diarrhea, all of which are indicative of Peutz-Jeghers syndrome, albeit without complications to date.

Discussion

Pathological Characteristics:

The cornerstone of this disease is the presence of multiple gastrointestinal polyps, which tend to grow, proliferate, and enlarge as the patient ages. Complications and subsequent symptoms arise primarily from these polyps, manifesting as inflammation, ulceration, hemorrhage, obstruction, and even malignant transformation. These polyps can induce a range of gastrointestinal issues including diarrhea, intestinal colic, melena, chronic anemia, intestinal obstruction, and necrosis. While biliary obstruction is rare, it remains a noteworthy complication.

Clinical Manifestations:

The polyps predominantly localize in the small intestine—most abundantly in the jejunum and least in the duodenum. Over the 14-year observation period involving three surgical interventions, we noted an evolution from localized small-intestine polyps to a more generalized distribution throughout the gastrointestinal tract. This highlights the progressive nature of the disease, characterized by subsequent growth and enlargement of these polyps.

Dermatological and Familial Aspects:

The disease also features specific melanin spots commonly observed around the lips, buccal mucosa, and extremities. The presence of these spots does not correlate with the severity of gastrointestinal issues but serves as a hallmark of the syndrome. Familial factors seem to be involved, as evidenced by the presentation of similar symptoms in one of the patient's children.

Diagnostic Measures:

The diagnosis leans heavily on the unique distribution of melanin spots. Barium contrast studies are instrumental in outlining the distribution, size, and morphology of the polyps. Although the symptoms can be non-specific and sometimes even absent—especially in children and during dormant periods—it's crucial to have early diagnostic procedures to prevent complications.

Surgical Considerations:

In this particular case, the primary lesion was at the duodenal papilla, making resection challenging. Due to the patient's severe condition, the primary surgical intervention was diversionary, aiming to restore continuity of the gastrointestinal and biliary tracts. Although we managed to control postoperative duodenal atrophy through drainage, a large number of polyps in various segments were left untreated, posing a risk for future complications.

Lessons Learned:

When resecting the intestine, careful planning is needed to preserve as much of the organ as possible, to maintain the patient’s digestive and absorptive functions. In this case, two prior resections left only 150 cm of small intestine, raising concerns about long-term functionality. Fortunately, no significant issues have arisen, offering an invaluable surgical lesson.

Long-term Prognosis:

With appropriate treatment, long-term survival is achievable, albeit often requiring multiple surgeries. The patient in this case study maintained a normal life and work routine over 14 years, despite undergoing three surgical interventions.

Summary

This paper offers a comprehensive overview of Peutz-Jeghers syndrome, delving into its historical context, pathological underpinnings, and clinical manifestations. Central to our discussion is a 14-year longitudinal case study involving a patient who underwent three major surgical interventions. This case provides valuable insights into not only the clinical course but also the familial aspects of this disease.

We note that complications arising from the syndrome often prompt medical consultation, commonly in young adulthood. Peutz-Jeghers syndrome is a congenital, incurable condition that necessitates multiple surgeries over the patient's lifetime. Despite this surgical burden, effective management can yield a relatively normal lifespan.

The paper aims to elucidate the pathological characteristics, diagnostic strategies, treatment modalities, and long-term prognosis of this complex syndrome. Our hope is that this work contributes to the broader understanding of Peutz-Jeghers syndrome, paving the way for more effective diagnostic and therapeutic strategies in the future.

References

  1. Zhong, Huawei. "Melanin spots ~ gastrointestinal multiple polyps syndrome." Chinese Journal of Surgery, vol. 6: 104, 1958.

  2. Chen, et al. "Recurrent polyps syndrome of gastrointestinal tract ~ melanin spots in the periphery of oral lip, buccal membrane, and fingers and toes." Chinese Journal of Surgery, vol. 13:244, 1965.

  3. Huang, Jiasi. Surgery. People's Health Press, p. 644, 1973.

  4. Huang, Jiasi & Wu, Jieping. Surgery (Volume 1). People's Health Press, p. 692, 1979.


Contributors:
Li Mingjie, Department of Surgery, Nanling County Hospital

Originally published in Journal of Bengbu Medical College, 1982; 7(3): 214.

 

from PEUTZ氏症候群 

 

【李名杰从医67年论文专辑】(电子版)

【李名杰从医67年论文专辑(英语电子版)】

Regular resection of left lateral lobe of liver for intrahepatic calculi

Surgical paper I

Regular resection of left lateral lobe of liver for intrahepatic calculi

Introduction

Intrahepatic calculi, otherwise known as stones within the bile ducts situated above the left and right hepatic ducts, are an often underdiagnosed but significant clinical entity. Over the past five years, our hospital has recorded 368 cases of primary bile duct stones, which constitute 83.4% of the 441 cases of cholelithiasis surgeries performed during the same time frame. Of these, 112 cases were identified as intrahepatic stones, accounting for 30.4% of primary bile duct stone cases. These statistics align closely with domestic literature on the subject [4, 5]. However, it should be noted that the actual incidence is likely higher, given the limitations in diagnostic capabilities. The distribution of intrahepatic stones within the liver is further detailed in Table 1.

Table 1        Distribution of 112 Cases of Intrahepatic Stones

left + right hepatic ducts + biliary pore

42

left + right hepatic ducts

6

left hepatic duct + intracholedochus

39

left hepatic ducts

6

right hepatic ducts + biliary pore

14

Other

6

Intrahepatic calculi present a unique challenge in diagnosis and treatment, often leading to misdiagnosis and unsuccessful interventions. Until recently, the condition has been marked by a cycle of recurrent episodes, multiple surgeries, and repeated failures in treatment.

In a concerted effort to enhance the treatment outcomes for intrahepatic calculi, our hospital initiated a new surgical approach. Between 1975 and 1976, we performed resections of the left lateral lobe of the liver in five patients. Following a period of 3 to 4 years of postoperative surveillance, the long-term therapeutic outcomes have been promising. This innovative approach has not only yielded good long-term curative effects but also provided valuable insights that have significantly improved our treatment protocols for intrahepatic calculi.

Clinical Data

The study sample comprised a total of five patients: two males and three females, ranging in age from 21 to 40 years. Among them, two patients presented with residual stones. Intraoperatively, all cases were complicated by choledocholithiasis—stones in the common bile duct. The primary location for the intrahepatic calculi was identified as the left lateral lobe of the liver, where varying degrees of fibrous atrophy were also noted.

Surgical Procedure

All surgeries were performed under general anesthesia with abdominal incisions. Resection of the left lateral lobe was the principal surgical intervention. A "T"-shaped tube was employed for external drainage of the common bile duct, or additional intrahepatic calculi were extracted using a "joining forces" technique.

Postoperative Outcomes

Two cases experienced complications, specifically delayed hemorrhage and abdominal infection. The hospitalization duration for these patients varied between 14 and 72 days. However, all patients recovered fully and were discharged. Postoperative recurrence of choledocholithiasis was noted in two cases, necessitating further surgical intervention supplemented by a choledocho-duodenal lateral anastomosis. Subsequent examinations revealed no presence of intrahepatic bile duct stones.

Long-term Follow-up

All patients were followed for a period of 3 to 4 years postoperatively and showed no signs of recurrence. Overall health status was reported as good. (For a detailed summary of the original medical records, please refer to Table 2). 

Diagnosis of Intrahepatic Calculi

The majority of surgeries for intrahepatic stones are performed to address biliary obstruction. Among the 112 cases in this group, 95 were complicated by common bile duct stones (84.9%). Previously, the removal of extrahepatic stones and restoration of biliary tract patency were considered sufficient for a "cure," supplemented by general treatment. However, this approach failed to account for potential adverse reactions arising from persistent intrahepatic infections. This oversight often resulted in repeated episodes and surgeries.

Diagnostic Methods

  1. Intraoperative Indicators: If the common bile duct is expanded by pigment stones or filled with sediment and the gallbladder is clear of stones, this suggests hepatogenic stones, warranting further examination of intrahepatic lesions.

  2. Visual and Tactile Examination: The liver's surface may exhibit localized hardness, paleness, and dome-shaped prominence, along with localized atrophy. In contrast, healthy liver tissue may show compensatory hypertrophy.

  3. Liver Abscesses: Multiple bile duct-derived liver abscesses often indicate intrahepatic calculi.

  4. Angiographic Evidence: "T" angiography may reveal negative shadows, such as a bean-and-pod pattern, suggesting intrahepatic stones.

  5. Postoperative "T" Tube Drainage: The presence of sediment-like stone deposition in the drainage bottle indicates a reduction in postoperative intrahepatic stones.

The Role of Left Extrahepatic Lobectomy in Treatment

  1. Minimal Surgical Trauma: This procedure inflicts moderate damage on liver function and minor disturbance on the body overall. When executed correctly, it solves most treatment challenges related to intrahepatic stones, ensuring short-term recovery and long-term satisfaction.

  2. Complete Elimination: It eradicates lesions and prevents ongoing infections and stone reformation due to poor drainage and bile retention.

  3. Alternate Exploration: The surgery allows for the exploration and removal of stones from other hepatic lobes, offering a different vantage point for tackling intrahepatic lesions.

  4. Convenience: Compared to intrahepatic cholangiojejunostomy, left lateral lobe hepatectomy is technically easier to perform.

However, it's crucial to note that simpler surgical interventions are more suitable for patients with toxic shock, severe systemic infections, or extremely compromised liver function. Relief of obstruction is better achieved with "T" external drainage.

Surgical Indications

The following cases are considered appropriate candidates for the surgical resection of the left lateral lobe of the liver for treating intrahepatic calculi:

  1. Multiple Intrahepatic Stones in the Left Lateral Lobe: Particularly when accompanied by fibrous atrophy, and when other hepatic lobes either have no stones or have stones that can be completely removed by other methods.

  2. Calculus in the Outer Lobe with Poor Drainage: Cases where the outer lobe has calculus, along with bile duct stenosis and poor drainage, making it likely that stone regeneration will occur if only the liver parenchyma is cut open for stone removal.

  3. Inaccessible Calculus at the Junction: Cases where there is calculus at the junction of the left inner lobe hepatic duct that cannot be removed through other means.

  4. Left Lateral Lobe Calculus with Abscess: Cases where an abscess is present along with the calculus in the left lateral lobe.

  5. Necessity for Roux-Y Longmire Surgery: Cases where the extrahepatic bile duct cannot be located due to inflammation or adhesion, or is too narrow to be shaped, thereby necessitating a Roux-Y Longmire procedure (anastomosis between the intrahepatic bile duct and jejunum) for drainage.

    Implementation Technique of Regular Left Lateral Lobectomy

    Preoperative Preparations

    • Anesthesia: Continuous epidural anesthesia is recommended.
    • Positioning: Patients should lie on their back with their right side elevated.
    • Incision: A right rectus abdominis longitudinal incision is advised. The xiphoid process is sufficient, and if necessary, the seventh costal arch can also be cut off and exposed through extrapleural enlargement.

    Hemostatic Techniques

    1. Local Blocking Method: After freeing the left lateral lobe, an assistant holds it or presses it against the costal arch, and the surgeon performs resection with minimal blood loss. This was the method used in all 5 cases.
    2. Hepatic Portal Block Method: The hepatoduodenal ligament is freed, and the hepatic artery and portal vein are blocked for 15 minutes, then relaxed for 5 minutes. This can be done safely and repeatedly.
    3. Other Techniques: Liver forceps, rubber bands, and the mattress suture method were not used.

    Surgical Procedures

    1. Ligament Resection: Cut several ligaments like the ligamentum cirrhosae, falciform ligament, left triangular ligament, left coronary ligament, and hepatogastric ligament.
    2. Vein Ligation: Place a needle 1 cm to the left of the second hepatic portal and ligate the left hepatic vein. Be careful not to damage the middle hepatic vein.
    3. Liver Capsule and Parenchyma: Cut the liver capsule 1 cm along the left side of the suspensory ligament and sever the liver parenchyma with a knife handle. The cut should be flat, not in a "V" shape, to avoid damaging the left inner vein.
    4. Vessel Ligation: Each vessel should be ligated individually.
    5. Stone Removal: The hepatic duct and common bile duct are jointly opened to remove the stones, followed by internal and external suturing or drainage.
    6. Final Steps: The mattress suture is limited to not crossing the suspensory ligament. Turn over the suspensory ligament to cover the liver section and fix it. Use subhepatic siphon drainage or negative pressure drainage.

Discussion

Stone Distribution and Diagnosis

The distribution of intrahepatic stones is not random but follows patterns influenced by anatomical and dynamic factors, particularly favoring the left lobe. Direct imaging techniques are ideal but may not always be practical, making clinical judgment during surgery crucial.

Left Lobe Calculus

Calculus in the left lobe often undergoes significant fibrous atrophy, losing much of its function. However, the anatomical boundary of this lobe is well-defined, facilitating a safer and more convenient hepatectomy.

Treatment Efficacy

Left lateral hepatectomy is effective in treating most hepatolithiasis issues. Chinese reports show a success rate of around 90%. There were recurrence cases, but these were not related to the liver, suggesting that more comprehensive internal drainage strategies might prevent such outcomes.

Treatment Goals

The key to treating intrahepatic calculi is to remove the focus, ensure drainage, and prevent new stone formation. Surgery alone may not be sufficient, and a multi-pronged approach involving other treatments may be needed to prevent recurrence.

Infections

Hepatolithiasis often comes with serious infections, which can lead to abdominal infections. Aseptic techniques should be strengthened to mitigate this risk. The use of intraoperative bile duct irrigation should be carefully considered as it can spread infections.

Blood Transfusion

The necessity of blood transfusion is not emphasized; for generally healthy patients, it can often be avoided.

Etiology

The high frequency of intrahepatic stones, particularly bile pigment sediment-like stones, is not yet fully understood. However, it appears to be linked to biliary ascariasis and subsequent infections by Gram-negative bacteria. These factors contribute to the formation of stones with various cores, like parasite cadavers, making it an important subject for preventive medicine.

Summary

The paper summarizes the treatment and follow-up of 5 patients who underwent left lateral lobectomy to address intrahepatic stones. It delves into the surgical indications, the benefits of this particular surgical approach, the techniques employed, and the precautions that should be taken. One of the key takeaways is the recommendation to combine left lateral lobectomy with other methods like "reunion" for stone removal or incisions in the liver parenchyma. Coupled with the establishment of "valveless" internal drainage, this multifaceted approach aims to eliminate infection and prevent the recurrence of stones. The paper concludes that this strategy offers a viable treatment alternative for the complex issue of intrahepatic stones.

References  

  1. Qian, Wenzhi.  Preliminary experience in treating hepatolithiasis by intrahepatic cholangiojejunostomy. Chinese Journal of Surgery 18221- 1965
  2. Meng, Xianmin. Hepatectomy. Shanghai Science and Technology Press, Shanghai 1965
  3. Han, Yongjian. Liver Surgical Anatomy.  Shanghai Science and Technology Press, Shanghai 1963
  4. Huang, Zhiqiang. Hepatolithiasis and its treatment. Chinese Journal of Surgery. 91716-1961
  5. Ran, Ruitu. Surgical treatment of intrahepatic bile duct stones. Chinese Journal of Surgery, 9:216-1961
  6. Zhou, Hongquan.  Discussion on etiology and treatment of hepatolithiasis. Chinese Journal of Surgery 50(8):501-1964
Li Mingjie, Department of Surgery, Nanling County Hospital

This article was published in Journal of Wannan Medical College, Wannan Medicine, 1980, 13:51  and Domestic Medicine Surgery Volume (Part 1), 1981, 39

 

 

from 肝左外叶规则性切除治疗肝内结石

【李名杰从医66年论文专辑】(电子版)

【李名杰从医66年论文专辑(英语电子版)】

 

Dad's medical career

Appendix: by Wei li

Dad's medical career

Dad didn't have a chance to enter medical college, instead he went to a junior medical school.  However, the achievements he has made in the past 40 years of medical practice are beyond the reach of most of his career peers from college. 

The excellence in his amazing career depends on his being bold as well as meticulous, being diligent in practice and studying hard.  I remember when we were young, we used to directly go to the operating room to look for our parents when we returned from school.  Dad worked very long hours a day, and when he came home, he plunged into medical books preparing for the operations next day.  It was rare for him to have time for a full rest.  Over the years, Dad built his fame as surgery master.  People seeking his medical treatment came in an endless stream.  Even when the relatives of the surgical director of the hospital at the next higher level need surgery, he would send them to my father for the peace of mind.

Doctors were well respected, but they had a fixed salary, barely making the ends meet.  In Mao's time, wages and prices remained unchanged for decades.  My dad’s monthly salary then was 46 yuan, and my mother 43 yuan, so our family income totaled 89 yuan, to maintain a family of six (us 3 children plus my grandmother) for basic food and clothing, it was difficult to have any savings for emergency.  Most people lived a poor life in those days, so we never felt we also had a hard time then, although for every meal, the entire family only had one or two small dishes besides rice.   Anyway, everyone was struggling, and there were still many people who did not have enough rice to feed the family.  Some could only afford porridge or dried sweet potatoes.   Dad's problem is, where could he save the money for medical books he badly needed?  Those big and thick professional books, such as Surgery and Osteology, are expensive, but they are must-have.  Who would have thought that many medical books were actually bought by my father’s selling his blood without telling the family. 300cc at a time, the price then was 30 yuan (to save 30 yuan would otherwise take half a year with strict budget).  Once, my mother was very angry when she found out my dad had donated blood for covering the cost of a book.  Dad was very thin then, and Mom was worried that his blood donation would harm his health.  But my father always argued that people have hematopoietic mechanism, and it's okay to lose some blood.  However, is there another way out?  No matter how skilled you became, you simply had no way of making extra money.  I remember that when the operation lasted long into late night, the subsidy for prolonged night work at that time was only 20 cents, or a bowl of free shredded pork noodles was provided (mom and dad would not consume the delicious noodles by themselves, but would always bring them home to feed us). 

It is true that each era has its own way of life.  However, it was still hardly imaginable that a medical doctor who enjoys a high reputation and well recognized medical skills could not afford his own medical books unless he exchanged them with his own blood.  This kind of thing could only happen perhaps in the Mao’s China.  It can't be said that Dad didn't catch up with good times.  From the perspective of career pursuit and spiritual satisfaction, the specific conditions of that specific era gave Dad a rare platform for practicing his wisdom and skills to the fullest extent.  The grass-root county hospital he served was like a blank sheet of paper for drawing, faced with a steady stream of endless rural patients who had always lacked medical care and facilities. These patients could not afford to be transferred for treatment in primary hospitals, so they had to try the county hospital at best, or quit any treatment leaving themselves to fate.  Dad was one of the founding members of the county hospital.  He had full autonomy and worked like crazy to cope with the endless incoming cases.  For years, there were a series of operations almost non-stop every day.  I knew a young doctor who was tired of practicing medicine because he could not see any career future limited in his rural clinic, and changed his career to become an English teacher after reentering a teachers’ college.  However, when talking about my father's medical skills, he was full of admiration: "Do you know your father is the greatest doctor in the world. Your father is able to perform major surgeries that are not commonly performed even in larger hospitals." He explained to me some of the highly complex cases my dad has dealt with, which I did not fully understand, but I knew that for decades my father had been continuously challenging himself and mastering more and more complicated procedures. Recently, when I asked my father if there were any surgeries he wanted to perform but had not yet been able to, Dad told me that he had pretty much done everything that could be done in his practice, except for some types of operations that were out of reach, such as microsurgery and replantation of severed limbs, which require expensive equipment and facilities that a county hospital simply could not afford, there were no such conditions for pursuing these.  

It is worth noticing that in many cases, even very poor farmers could also enjoy surgery services in grass-roots hospitals like the county hospital my father served.  At that time, the fees for minor operations (e.g. appendectomy, etc.) were less than 10 yuan a surgery, those for medium-level operations (e.g. gastrectomy, etc.) cost tens of yuan, while those for major operations (e.g. surgeries involving heart, brain, etc.) were about a hundred yuan.  Of course, it's not easy to save enough money for such costs, but most people have come up with a way to manage that as emergency needs.  For extremely poor households, there was a way to apply for government subsidies at the Civil Affairs Bureau.   This part of the low-cost medical system with socialist subsidy policies in Mao’s time is worthy of praise.  The fundamental reason for the low fees is, of course, the very limited basic cost for human resources: doctors and nurses were state employees, getting a modest fixed salary, with  few extra expenses. 

Speaking of surgery, I myself still have my father's “magic work” on me.  It was the time when I was about ten years old.  One day, shortly after breakfast, I suddenly had a terrible stomachache.  Dad came to check, pressed his hand on my right lower abdomen and asked if it hurt.  I said, "It hurts".  He suddenly pulled his hand back, and I immediately felt a sharp pain, and could not help with tears out.  Dad told me that this is called "rebound pain", which is a typical symptom of acute appendicitis.  He told me that I needed an immediate surgery and soon brought me to the operating room before noon.  I had been used to seeing operations since I was a small child, knowing that appendectomy is a minor operation, and I should not be afraid of it at all.  But when I was really sent to the operating table, I felt I should not be rushed to it.  What if it was a mis-diagnosis?  In that case , would I undergo an open operation for nothing?  I felt just fine in the morning before breakfast. After drinking half a bowl of porridge, I suddenly had a strike of stomachache.  I did not even have a blood test or other clinical tests.  All diagnosis was based on my father’s checking my lower abdomen with hands, was that sufficient?  I simply could not drive my suspicion away and was very reluctant to face the coming surgery.  Of course, all these were my over-anxiety.  My appendix extracted in the surgery was swollen like a carrot head.  Because the operation was timely, it hadn't festered yet.  Many surgeons don't operate on their loved ones for fear of being too nervous.  But dad would not trust others, so he insisted on doing it himself, with my mother as his assistant.   Usually, if conventional spinal anesthesia or epidural anesthesia were used, he could take his time, but dad insisted on using only local anesthesia for the sake of small postoperative response and fast recovery.  So I was conscious of every process of the operation clearly.  Most similar operations then often left a few inches of incision on the skin, but my father only gave me a small incision of one or two centimeters (only two stitches used after closing my abdomen), barely enough to insert a finger through.  Moreover, unlike most incisions, Dad used crosscutting, which makes the operation more difficult to operate.  Dad said that cross-cutting conforms to the natural lines of human abdomen, and the scar would not show up after healing (indeed, I have seen the scars of other vertical cutting operations, and they stand out there thick and red, long after healing, which looks really ugly.  In contrast, mine was hardly noticeable).  Of course, this operation was very successful.  I went home the same day, and the next day I was able to get out of bed and slowly walk around.  However, there was a real pain during the operation with only local anesthesia, and I cried and shouted, which put a lot of pressure on my father.  The pain was most serious when Dad’s finger tried to get to the inflamed appendix, which hurt even if it was not touched, not to say being pressed.  Fortunately, it didn't hurt for a long time before my father caught it and quickly made up for some additional anesthetic.  My father reflected the procedure later on, and said that despite all his efforts, the place where he cut the knife in was slightly off the target, which unfortunately made me suffer more pains.  Local anesthesia should have been fine if the incision were enlarged, an easy way to go, but Dad insisted on making the incision as small as possible, and did not want me to leave a permanent big scar for life.  Year later, I told my daughter this story, and she tried to spot my almost invisible surgery scar and exclaimed, "Grandpa did a terrific job! Grandpa's craftsmanship is out of the world! ”   From then on, when she had a stomachache, she often shouted, suspecting that she had appendicitis.  I felt relieved when I found that there was no "rebound pain".  She also said that if she had appendicitis, she would fly back to Grandpa, because the doctors in the United States couldn't be trusted: they had only operated a limited number of cases, and my grandpa had operated tens of thousands of surgeries in his life! 

Dad often paid on-call visits to rural clinics and farmers' homes (as director of obstetrics and gynecology, so did my mother).  Many cases needed emergency surgeries on the spot, no matter what the conditions were, they had to be carried out to save lives.  Many rural areas had no electricity, so flashlights were collected together over the an operating table.  In the second year of the Cultural Revolution (1967), the two factions of grass roots organizations were divided into conflicting groups, often with friction, sometimes using fire arms.  In the beginning, it was street fighting, using steel knives and the like, and at the later stage, they used real guns.  Our county town became a war zone.  The county hospital was in a semi-paralyzed state, and it was located in the area controlled by the group named "Sweeping the Black Line" (a more radical mass organization).   Mom and Dad were closer to the less extreme group so-called royalists ("royalist" means opposing the struggle against veteran cadres), but they would not participate in their ideological and political activities.  The commander-in-chief of this group used to be the uncle next door, tall and robust.  In my memory, after serving as the commander, he often wore a wide belt around his waist, carrying a box gun, and staged to be very heroic.  One day, he sent someone to our home, quietly inviting our whole family to the base camp of his faction as they urgently needed medical experts to treat the wounded in the warfare.  When we were settled down, my father set up a wartime operating table in the camp, just like Bethune's battlefield hospital, which also saved many lives. 

In years of peace after that “civil war”, the white ambulance in the county hospital used to carry mom and dad often together with us children for on-call emergency visits, having run around every corner of the county.  If the call was from a nearby village, the visit was also on foot or by bike.   I still remember when I was six or seven years old, my whole family moved to Hewan, a remote small mountain town, to support a rural hospital for one year.  Dad often rode his bike in the night for home visits and sometimes he took me with him on the bike.  It was always so dark, often passing one or two cemeteries, with a cold wind blowing overhead.  When we entered a village, there were always dogs barking one after another.  I hid in my father's arms in the front seat of the bike, too afraid to dare open my eyes.   After treatment, under the dim oil lamp, the host often boiled two eggs with brown sugar, and served them steaming hot to entertain us for appreciation.  Then, they would use flashlights to send us out of the village, and I was often fast asleep on the way back before we got home. 

Dad has always hoped that we children study medicine and follow his footsteps.  If nothing else, wouldn't it be a pity that the shelves full of medical books accumulated over the years have no one to carry on?  Unfortunately, none of us four children ended up following this path.  My elder brother and I were the first college students after the Cultural Revolution (Class 1977).  In that year before the entrance exam, following the wishes of our parents, we both placed "Anhui Medical College" as our second choice.  As for the first choice, my brother took the initiative to apply for "Nanjing Aviation Institute".  At that time, I didn't have my own opinion, so long as I would enter a first-class university to study the then popular physics.  So I followed my father's advice, set  a  popular physics major plasma as top choice for the top school "University of Science and Technology of China”.  We were in an age when we were convinced that “good knowledge of maths and physics would carry us all over the world to achieve anything we want".  I don't know what plasma was, but I always felt that only such an unfathomable major would be qualified to surpass my father's career of medicine practice.  As a result, my brother got his first wish   honored and went to pursue his dream of aviation with satisfaction.  But all my choices failed to bear fruits, and I was forcibly "assigned" to the English Department of Anqing Normal University.  What a disappointment and shock to me!  Although I didn't do very well in the college entrance examination, I later learned that my scores had reached the standard set by "Anhui Medical College” and I should be qualified for my second choice.  The bad thing is that I "added" foreign language in the test list in the hope for enhancing my college competition.  But in the first college entrance examination after the Cultural Revolution, foreign languages were not a compulsory test item, nor were they included in the total score that determined their destiny.  The reason was simple: although college had shut down for nearly ten years to have accumulated 10 times of candidates competing for colleges at the same time, many people never learned any foreign languages in school.  If colleges insisted on testing foreign language as compulsory, more than half of the candidates would be excluded from the radar.  So it was decided to be an elective test item.  I myself would not have dared to take the English test if I hadn't followed the English learning programs of Anhui and Jiangsu radio stations for many years.  I had hoped that given the same conditions, my additional test on English would help me to be admitted first for my choices.  Who would have thought that after the Cultural Revolution, there was a serious shortage of foreign language major candidates in the liberal arts, so some science and engineering students who took additional foreign language tests were simply transferred to the liberal arts pool.   That is how foreign language which should simply be a tool for other specialization became my major subject.   In those days, the popular mentality favored science majors.   After being forced to enter the liberal arts foreign language department, I always felt that I had "strayed into the wrong side door".  With that, I decided to insist on further self-study of advanced mathematics and Linear Algebra for another two years after entering college, which unexpectedly laid a foundation for my future interdisciplinary development of arts and sciences in my master’s program computational linguistics.  Looking back, I think it was fortunate that I didn't get into medical school as I had hoped, otherwise there would only be one more mediocre doctor trained in the world.  I do have some perseverance in studying, but I lack my father's courage, ingenuity and boldness which are required  to be an outstanding physician.  I would not have been able to be even close to Dad.  I have seen many admirable elders and newcomers in my life and career, but I always admire my father the most.  He set up an example of excellence way beyond our reach.

Dad is now semi-retired at home, still living a very simple life, in an orderly and healthy way.  Unlike most other old men around 70 years old, he still keeps a keen interest in new things, and is more familiar with computers than many young people.  He enjoys a solid knowledge of professional English for many years, and his general vocabulary is comparable to that of myself whose major is English.  The development of all of us children is his greatest comfort.  The little stories of his grandchildren's growth brings him great joy. 

The previous work is a debriefing report written by my father ten years ago for applying for the promotion as chief physician.  Between the lines of many medical terms and figures, many past events of Dad’s medical practice and life come back to my mind, as if it were yesterday. 

 

《朝华午拾:爸爸的行医生涯》

【李名杰从医66年论文专辑(英语电子版)】

 

Career Path and self review

In support of application for Deputy Chief Surgeon, 1987

Editor’s Comment: This piece of writing submitted by my father 35 years ago is a review of the achievements and hard work in his first 30 years of medical practice. This stellar and unique report card explains how a doctor in a grass-roots hospital has been tempered into a powerful ‘iron man’, becoming an all-skill expert practicing almost all major medicine areas, extremely rare in a modern society.  In helping compile the collection of his own medical papers and in reviewing the 66-year journey, my father feels extremely grateful and proud. Dad said, his growth depends largely on “one book and two mentors”. This book refers to Maingot's Abdominal Surgery, which is a biblical surgical masterpiece. Dad said: At that time, the price of this book was 10 yuan, which was 25% of my monthly salary. It was a treasure of all my belongings! 

One of the two tutors was Dr. Meixian Min, the surgical authority in Wuhu superior hospital, whose theory, technology, character and demeanor were praised by everyone!  The other is Dr. Jingbin Xu, an authoritative professor of orthopaedics in China. My father studied orthopaedics with him at the 127 Hospital of the People's Liberation Army and became his accomplished disciple. About Dr. Min, Dad recalled two episodes he has cherished most.  Dad said: 

Once, he had me preside over an extremely challenging operation. When I came to the operation table ready for the surgery, he said, "Maybe you can't get off the table successfully. Everything off the table  is mine!"  It means all the aftermath, I do not need to worry about, and he will take care of everything. Who can match this spirit of responsibility! Another thing he said is also very memorable.  Before I moved to Wuhu, I came to see him, he said, "Knowing your recent situation, I suggest that you come to join me, in department of either surgery or orthopedics, better in surgery as it has a wider range and would benefit your further development. As long as your current employerNanling agrees to let you leave, I’ll take care of all logistics on the accepting side, including the health bureau, personnel bureau and hospital authority. Ours will be the Second Affiliated Hospital of Anhui Medical University, the provincial level hospital, which should be beneficial to your future promotion! "  He was very sincere and his favor was out of pure treasuring for talents. Apart from the career relationship as my mentor, there was not much personal relationship between us. Along the journey of practicing surgery, I always turned to him for advice once I came across challengies, and he acted always as my direct supervisor. It was also his key evaluation that helped my smooth promotion to the title Attending Physician.  He was the chief examiner in the promotion committee, and he evaluation was decisive. At that time, he said to me: “you can apply for either surgery or orthopedics for this promotion”.  The implication was that I was qualified for both subjects. That was 1981, not long after the Cultural Revolution. The entire Nanling had only seven people promoted to Attending Physicians, that is, less than half of the applicants made it.  Your mother and I both succeeded in the promotion list, which caused a stir effect in our community. At that time, professional titles were highly respected in the society. With the title of attending physician, one can enjoy all kinds of preferential treatments.

Mingjie Li, a full-time worker, graduated from the medical class of Wuhu Medical School in 1955.  In March 1956, he joined Nanling County Hospital. In 1960, he was sent to study radiology in Wuhu District Hospital for one year, and then returned to the hospital to establish the radiology department.  Since 1961, he has been mainly engaged in clinical surgery (during which he had worked concurrently in radiology for two years).  Since 1968, he has been the principal surgeon of major surgery in the hospital.

In 1973, he took part in an advanced training course in orthopaedics, and studied orthopaedics for more than one year under the guidance of Professor Jingbin Xu, an expert in orthopaedics at the 127 Hospital of the People's Liberation Army and editor of the Chinese Journal of Orthopaedics.  He obtained a certificate for the completion of the course.  Meanwhile, he was selected by the Foreign Affairs Bureau of the province as preparatory personnel for the foreign aid medical team waiting to be sent abroad.  On December 1, 1981, he was promoted to the title of Attending Surgeon. At that time, he served as Director of Nanling Branch of Medical Society.  In August, 1985, he was transferred to Wuhu Changhang Hospital, where he worked as an attending surgeon and orthopedic surgeon.

Since the medical association resumed its activities after the Cultural Revolution, I have participated in, and submitted papers to, the first, second and third annual conferences of orthopaedics and the first and second annual conferences of surgery in Anhui Province.  My papers were printed in the conference proceedings for research exchange.  I have also submitted papers to the first academic conference of obstetrics and gynecology in Anhui Province.  I have been involved in a variety of academic activities at the prefecture, city and county levels.  I have served as a lecturer in the county health school, teaching courses in anatomy, physiology, surgery and orthopedics.  I have been supervizing numerous medical college interns for many years.  I have been studying professional English for more than 10 years.  In 1980, I took part in the correspondence course of "Clinical English Learning" administered by Jiangsu Health Department for one year. Upon graduation, I won the first prize for the National Translation Competition.  I have translated a number of professional papers.  I can read and translate English books and journals, and write English abstracts for my own papers.  I have published numerous papers in medical journals at all levels, and in 1980 I was awarded the title of advanced scientific and technological worker in our county.

In the past two years since I joined Changhang Hospital, according to the limited cases encountered in our hospital, I have performed subtotal thyroidectomy, superficial parotidectomy, radical gastrectomy for gastric cancer, rectal cancer and breast cancer, and numerous cases of gallbladder, biliary tract and intestinal operations.  In addition, I have treated cases with spinal canal decompression, spinal cord exploration, myelography (Amipaque), closed penetration of triangular nail under fluorescence of femoral neck fracture and other osteopathy operations in orthopedics.  All these cases have achieved good results.

Earlier in my career, I served in Nanling County Hospital surgical department for nearly 30 years as a front line   physician of clinical practice. As a principle, all kinds of cases should be solved on the spot. Therefore, my practice covered a wide range, including orthopedics, urology, thoracic surgery, obstetrics and gynecology, ophthalmology and otorhinolaryngology, which are described below.

General surgery:

Surgeries performed include epatectomy, liver repair, ligation of proper hepatic artery, and a large number of biliary surgery and various biliary and intestinal drainage,

Additionally, a comprehensive array of biliary surgeries and assorted drainage techniques for both the biliary system and the intestine have been performed. These techniques include sphincterotomy and plasty of Oddi's sphincter, as well as various forms of anastomosis involving the common bile duct and duodenum. Procedures such as Roux-en-Y jejunostomy and multiple subsequent operations for recurrent hepatolithiasis are also among the interventions undertaken

such as Oddi's sphincterotomy and plasty (括约肌切开、成形术), side-to-side and end-to-end anastomosis of common bile and duodenum and its low hole anastomosis, Roux-y jejunostomy, second, third and fourth operations for recurrent hepatolithiasis. Incision and stone removal of liver parenchyma, intrahepatic bile duct stricture plasty, intrahepatic bile duct bypass, a large number of cases for gastrointestinal surgery, radical gastrectomy for gastric cancer (R1R2), total gastrectomy, radical resection for rectal cancer (Miles Bacon Dixon operation), intestinal obstruction, colon cancer, hernia, hemorrhoids, appendix, etc. A case of Hirschsprung's disease, congenital omphalocele and Pcutz-Jegher Syndrome underwent three operations in 14 years, including hyperthyroidism surgery, radical mastectomy (including super radical mastectomy), splenectomy (including giant brand 含巨牌), splenorenal vein anastomosis, portal azygos disconnection, internal drainage of pancreatic cyst, focus clearance and drainage of abdominal adenitis, PTC and retroperitoneal oxygenation.

Extrathoracic:

Resection of carcinoma in the middle and lower esophagus (including supraarch anastomosis and thoracic roof anastomosis), lung repair, pneumonectomy, septal hernia repair, and closed thoracic drainage.

Urological surgery:

Surgical procedures on the kidney such as removal of the kidney, stripping of lymphatic vessels in the kidney, removal of stones from the kidney through an incision in the renal parenchyma, removal of tumors in the kidney, removal of stones in the ureter and bladder, realignment of the urethra in case of trauma, vasectomy, transplantation of the ureter, removal of one or both testicles, treatment of cancer on the penis, and repair of a congenital defect of the urethra called hypospadias.///Nephrectomy, renal lymphatic stripping, pyelolithotomy, renal parenchyma incision to remove stones (肾实质切开取石), renal embryonic tumor resection, removal of ureteral and vesical urethral calculi, urethral trauma realignment, vasectomy and anastomosis, ureter transplantation, orchiectomy, penis cancer radical cure, hypospadias repair.

Obstetrics and gynecology:

All operations involved, including Cesarean section (classical, lower segment, extraperitoneal surgery), total hysterectomy (abdominal, vaginal), tubal ligation (abdominal, vaginal), vaginal wall repair, uterine isthmus incision to obtain the fetus, induction of labor, fetal debris, ovarian tumor resection, vesicovaginal fistula repair, cervical cancer pelvic cleaning.

Orthopedics:

Manipulation and surgical treatment of limbs’ bone, joint and spinal trauma, including reduction steel plate internal fixation and bone grafting for spinal fracture and dislocation, internal fixation (opening and closing) of femoral neck fracture with three-wing nails, and lesion removal of bone and joint tuberculosis, including surgery for tuberculosis of neck, chest, waist, sacral vertebra, hip, knee, ankle, shoulder, elbow and wrist joint, one-time operation for thoracic vertebra tuberculosis through pre-thoracic approach,  with lesion clearance, spinal canal decompression and anterior bone grafting, spinal cord tumor extraction, lumbar intervertebral disc extraction, myelography (iodine oil and iodine water), bone tumor (benign and malignant) surgery, meningocele repair and some orthopedic operations.

Ophthalmology and ophthalmology:

Tonsillectomy, radical correction of maxillary sinus, turbinectomy, nasal polypectomy, mastoid incision, cataract, artificial pupil, dacryocystectomy, nasolacrimal duct anastomosis, enucleation and strabismus correction, trichiasis, pterygoid excision and burial, etc.

 

Professional growth and innovation efforts

The original county hospital where I worked for nearly 30 years is a medical center with a population of 500,000 in the mountainous area of southern Anhui, and its surgery has an exclusive market. Although in the early 1960s, when I entered the early clinical stage of surgery, the conditions and my skill level were both very limited, I had to work hard to face all kinds of diseases related to surgery. There were many surgical opportunities and a wide range of operations. Environment trains people, pressure urges them to advance.  I managed to study hard and practice hard, and made rapid progress in practice.

The famous Maingot’s work "Abdominal Surgery" has benefited me a lot with intensive reading and digesting.  At that time, the incidences of intestinal obstruction were widespread, especially in the years of famine.  There were hundreds of such cases in a year, which laid the foundation for me to break through the basic theory of surgery and practice of lower abdominal surgery.  In 1964, I marched into the upper abdomen practice.  On the basis of dozens of stomach and gallbladder operations, I was appointed to lead a team for rural roving medical treatment in the countryside in 1965.  In 100 days, more than 600 operations of various scales were performed, including 121 laparotomy operations, in which 25 were upper abdomen operations, including stomach, gallbladder and uterus operations.  By this time, I had mastered the epidural anesthesia technique in advance, which created favorable conditions for these operations.  In the following year, I was sent to lead a team to set up two medical branches in Yijiang and Hewan successively, serving as business leader and continuing to carry out surgical operations.  In 1968, I was appointed as the head of the major surgery department of our county hospital, in charge of the treatment of all surgical patients. According to statistics, nearly 100 cases of gastric and biliary operations were performed in our hospital every year in that period.  Over the past decades, I have accumulated experience from both positive and negative aspects through a large number of operations, which also involves a process of continuous exploration and innovation.

In 1973, I participated in the restoration and reconstruction of Wuhu District Hospital after the early tubulance of Cultural Revolution.  While studying orthopedics, I also helped to perform numerous surgical operations, under the guidance of the director of surgery. Orthopedic specialty was also systematically studied and mastered.  I learned the most from Director Meixian Min and Professor Jingbin Xu, who were my two mentors in surgery and orthopedics.

Learn to swim in swimming

The recurrence and reoperation of cholelithiasis prompted me to be eager to update my examination methods and operation methods.  Inspired by the literature, I shifted my focus from simply dealing with extrahepatic bile duct problems to paying special attention to the discovery and examination of intrahepatic stones, hence a better understanding of intrahepatic bile duct stenosis.  Shortly after the 1980 Provincial Surgical Annual Meeting, I administered PTC, which dramatically improved the blindness in the past practice.  The operation methods also expanded to hepatectomy and liver incision for stone removal.  Combined with Finster operation plus Oddi sphincterotomy, Roux-en-y operation, posterior duodenal choledochoduodenectomy, hollow anastomosis of distal common bile duct and other internal drainage methods, the curative effect was greatly improved and the re-operation rate was reduced.

In our county, early local schistosomiasis portal hypertension was very common, our treatment ranged from early gastric circle and omentum to liver and kidney, to portal azygos disconnection, and finally to splenorenal venous shunt in 1976.  In order to prevent short bowel syndrome after a large number of bowel resection, I performed intestinal anastomosis with interposition of reverse peristalsis segments, resulting in good effect.

I had frequent on-call visits to the countryside to rescue liver and spleen injuries and ectopic pregnancy.  In order to solve the critical problem of blood source difficulty, my innovative and careful self-blood transfusion approach played a positive role.  For example, in 1969, I was sent 60 miles away to visit a 13-year-old child with rupture of the central liver, which needed to be repaired through the chest.  During the 4-5 hour interval while waiting for the ambulance’s return from the county hospital to bring the anesthesia machine, I practiced rein fusion of up to 1000 ml of abdominal liver blood repeatedly for the first time, and finally won the operation opportunity.  The postoperative recovery was fairly smooth, but 16 days later, the patient was complicated with massive hemobilia, treated with ligation of inherent hepatic artery, also for the first time.  Finally it was cured.  Having followed up to now, all is well with the case.

    Following the experience reported by provincial hospital in the First Annual Meeting of Obstetrics and Gynecology in 1980, I helped the Department of Obstetrics and Gynecology in our hospital to carry out the first 10 cases of extraperitoneal approach cesarean section and gained practical experience.  This became standard operation in our hospital.

After further study in the orthopedics trainee class, I changed the posterior approach of vertebral tuberculosis to the anterior approach for one operation, which greatly shortened the course of treatment, including one-time treatment through chest of thoracic tuberculosis complicated with paraplegia.  At the same time, interbody bone grafting was performed. In addition, lumbar tuberculosis was also treated with a trial operation to remove bilateral abscesses, together with bone grafting.  It was a success.  I also performed cervical tuberculosis surgery. This experience was reported at the first annual meeting of orthopaedics in our province.

Femoral neck fractures are common, complicated to handle and often ineffective. The original open triangular nail fixation led to   damage, easy to cause shock to the elderly, and often requiring blood transfusion.  After learning the experience from the Tianjin peers in 1979, I changed to closed nailing under fluorescence.  The patients had little burden, resulting in less pain, faster recovery and less cost. This experience was reported in the third provincial orthopaedic annual meeting.

I also advanced the spinal cord lipiodol angiography in the past to iodohydrography, which provided the basis for the diagnosis of intervertebral disc surgery, beneficial to the identification and monitoring.

In addition, I assisted the Ear, Nose, and Throat (ENT) department in performing a procedure called subchondral tamponade to help treat a condition called atrophic rhinitis by filling under the mucous membrane of the cartilage nose.  My report of this practice received rave reviews at the first annual meeting of the ENT in the province.

In summary, my professional growing process is primarily through improvement in massive practice and advance in technical pursuit. Long-term independent work facing all sorts of clinical practical cases, short of good conditions and nearby mentors, enables me to have developed the habit of independent thinking and turning to books and literature for help and insights.  Every time when a new operation is carried out, I feel it necessary to collect extensive information and review all relevant knowledge for contingency. This way, although the road has not been easy, the experience accumulated from practice proves to be fairly profound.

Mingle Li, Attending Surgeon, Wuhu Changhang Hospital, 19??

 

业务自传和工作报告

【李名杰从医66年论文专辑(英语电子版)】

Service beyond my hospital

Editor’s Comment: I have always felt that Dad is the modern Hua Tuo created by the times, which is basically unprecedented (except for Hua Tuo himself maybe) in terms of extensiveness in medical practice, the number of patients treated and the long service time.  Dad has been practicing medicine at the grass-roots hospital for more than 60 years (he is still on the job for half a day although he is in his eighties now).  In his long career, Dad has encountered various complicated situations. With his extraordinary intelligence, dedication and ingenuity, Dad demonstrated his expertise and professionalism to the fullest extent.  Dad has been both bold and cautious, knowing how to adapt to local conditions case by case, having saved countless lives with his comprehensive skills.  In a community where more than 300,000 people in the county had access to  only two or three surgeons, there was no clear division between surgery, gynecology, orthopedics and so on.   My dad made himself to be a general practitioner involving all major areas of clinic practice.  As my father said in his memoire, "My surgical life is the longest, with a large number of operations involving a wide range of surgical  areas (general surgery, orthopedics, urology, obstetrics and gynecology, nerves, facial features, chest, etc.)."  This is one piece of his more works written in 2011 covering his amazing undertakings in clinic visits beyond his hospital.  These stories can enlighten young doctors and encourage them to strike for their best. 

My surgical career has lasted for more than 50 years since the early 1960s.  Besides the three hospitals I have served as full time practitioners (Nanling County Hospital, Wuhu Changhang Hospital, and China Railway Bujiadian Hospital), I have been involved in dozens of external hospitals in "guest practice", including hospitals at all levels in Nanling and Wuhu, such as the Fourth Hospital, the Sixth Hospital, Xinwu Hospital, Matang Hospital, Jiangdong Hospital, Clinic at Smelter, etc.  My engagement also includes  on-call house visits, tour medical treatment in rural areas, various on-site surgeries and remote consultation as a visiting doctor.  This achievement is hardly heard of in terms of the number of number of operations and a wide range of subjects involved (general surgery, orthopedics, urology, obstetrics and gynecology, neurology, facial features, chest, etc.).  In fact, the number of operations performed beyond my own hospitals may well exceed the sum of the operations I have practiced in the three hospitals I have served. 

This situation of work overload continued until June, 2007, when my health entered an inflection point, with a red light on.  I was rushed to Wuhan Union Hospital for stomach cancer with massive bleeding, and had a total gastrectomy.   My gallbladder was also removed in the surgery  due to gallstones.  My postoperative recovery was reasonably smooth. Postoperative pathology: gastric Ca, poorly differentiated, involving deep muscle layer, all 18 lymph nodes around the stomach were negative, which can be described as "early stage". The operator said: no radiotherapy or chemotherapy is needed.  With this diagnosis, for the  sake of dealing with the cancer monster, it's a perfect ending, it's all over.  But my health was still hit severely with a long list of consequence.  I suddenly lost 15kg (from 70Kg to 55Kg). Although there were no common complications such as stenosis, reflux, dumping, indigestion, I felt sudden aging effects now that I have no bile and stomach.  Life entered the countdown, and energy and physical strength are much worse.  Physiologically, there is always something occurring of annoying discomfort or minor symptoms one after another.  Fortunately, I still can maintain the lowest level of normal "healthy" daily activity: I have been working in the first half of the day, and from time to time, I still manage to perform operations at the table for 3-4 hours non-stop.  From June to August last year, I made a trip to Silicon Valley, USA, where I visited my two sons and their families,  who both have a PhD background and serve the IT industry.  I endured the 14-hour flight journey fairly well.  So far, it has been more than 4 years since my operation, so I think I was lucky enough to have escaped the cancer.  However, what it left behind is a downhill path in life, and I know my future is limited.  So I need to cherish life more in the remaining time. 

After that incident, besides emergency call for surgery rescue several times, basically I stopped the out-of-hospital consultation practice, but the operations in my hospital have not stopped.  Nevertheless, surgery operations beyond my own hospitals accounts for more than half of my surgical career.  Here, looking back on the external visiting practice or on emergency calls to help rescue in the middle of other’s operations, there are some remarkable episodes worthy sharing.

It is said in the scientific and technological circles that scientific and technological talents should be encouraged to take more external posts or jobs, in order to fully tap the valuable human resources to serve the society.  But the current "practice" following the on-going policy is to stick to one post, in the fixed discipline for fixed jobs, with no felxibility allowed.  However, in today's market economy, it is not uncommon for experts to take advantage of the needs for undertaking multiple external jobs for extra financial benefits,  making visiting experts or guest doctors lose their original glory.  I have experienced the social transformation and different needs of various times in different periods over a much longer time.  In contrast, my guest practice was quite unique. 

During the 29 years (1956-1985) of working for Nanling County Hospital, the expert human resources of the society were extremely scarce, with very few doctors and even fewer surgeons serving a large population.  In fact, for many years there were only two or three surgeons who were counted on to meet the needs for solving the difficult surgery problems in a county with a population of more than 300,000 residents.  That is to say, all the surgical patients in this population basically need to be treated by these two or three people.  Prohibited by the economic and traffic restrictions at the time, there was very little possibility to outflow the patients elsewhere.  Furthermore, in addition to those who manage to come to the hospital, there are many of them who cannot make to the hospital in emergency.  It is inevitable to make numerous house visits, consultations and on-site operations.  Especially after 1968, as the head of our surgery department, I had to make more frequent house visits and all kinds of consultations for diagnosis. 

Here's a fun episode.  At that time, there was only one ambulance in our hospital, driving within 20 miles an hour at its best on those rural sandy roads. Many times, it was only me and our driver heading for an emergency house visit to the rural area.  Over time, although I didn't attend any driving class, I managed to have learned to drive, without a license (at that time, the traffic rules were lax and there were few vehicles on the country road anyway). Over the subsequent few decades, I drove at least 10,000 kilometers to make house calls, with a driving experience of more than 30 years, comparable to a full-time driver.  It is mainly my health and age following my last operation that makes me miss the emerging driving era as a legit licensed driver. 

That was the era of "serving the people", and there was never a personal benefit of house visiting and consultation for any out-of-hospital surgery. When we needed to invite experts from the superior hospital to come for consultation on difficult cases, it was the same.  Their coming to support was counted as a business trip then, only to reimburse their travel expenses.  They needed to leave 20 cents to cover the cost of the meal. In Mao’s era, no matter how famous a doctor is, there was no way of having any extra-salary income. 

1. Rural itinerant medical treatment 

During the last three months for 100 days in 1965, as captain leading a rural itinerant medical team of 5-7 people, I performed 612 operations, major or minor, in Yandun Commune, Nanling.  Among them, 121 people underwent laparotomy, including stomach, intestine, gallbladder, uterus, hernia, hemorrhoids, thyroid, kidney, ureter, bladder, orthopedics, ophthalmology and dentistry.  One afternoon, while there was availability of an anesthesiologist on site, I operated on three consecutive cases of vaginal hysterectomy plus pelvic floor repair and reconstruction.  The high rate of this disease, often third degree uterine prolapse (or pelvic floor hernia), was in fact incurred as side effects of sustained malnutrition from the notorious great famine in 1960 China.  This is unbelievable work efficiency, not to mention that everything was operated on a temporary "operating room" in a remote commune clinic.  That day, operations lasted non-stop until three o'clock in the morning, and more than ten other operations were also performed. 

There is a middle-aged woman who suffered from intestinal perforation of typhoid fever complicated with peritonitis (such infectious diseases were prevalent at that time, but very rare in recent years).  I treated her with intestinal resection.  She was penniless and there was no charge on her treatment.  Furthermore, after she was discharged from hospital, I rode my bike to pay her a house visit in her rural home in Qingyangmu town for the follow-up and condolences, with some donated gifts gathered from physicians ourselves. This was a trend in answering the call from Mao on serving the “poor and lower-middle peasants”.   It also reflects the original holy glory for medical practitioners as "angels in white". 

There was a case of incomplete abortion with massive bleeding, facing a crisis every minute.  I and a midwife rushed to her home at Sanxing Brigade to give an emergency uterus cleaning with rapid fluid replacement, which saved her life. 

Another case of vesicovaginal fistula was repaired by my operation, and discharged with recovery after 12 days.  This success initiated this kind of operations.

2.   First aid visits

Here are a few cases of first aid visits to share. 

That was 1968.  A 13-year-old boy from a remote mountainous village Yashan fell from the back of a cow, and his right liver ruptured, causing massive abdominal bleeding.  I rushed in our ambulance to the Hewan health center where I had to open his chest to complete the operation.  There was a need for blood transfusion.  I had to send the ambulance back to the county town (at that time, this was the one ambulance we had) to fetch the anesthesia machine and a blood donor.  This mountain road was in a very poor condition, about 30 miles away, and it happened to be foggy day in the mountainous area.  It ended up taking more than 4 hours for the return trip.  I simply could not wait any more.  As a last resort, I decided to have the accumulated blood boldly extracted from the patient’s  abdominal cavity for the first time to save the case.  The self-transfused blood amounted to 1700 ml.  Here it also involves a theoretical question whether the blood mixed with bile can be re-transfused safely, which  was debated in the community and also finally affirmed in subsequent literature later on.  The transfusion helped to maintain the hemodynamic operation during the “waiting" time, and enabled the general anesthesia thoracotomy and liver repair surgery on the spot.  The postoperative recovery was fairly "smooth".  But 9 days after the operation, just as he was supposed to be discharged the next day, the complication of intrahepatic biliary tract hemorrhage occurred.  The hemorrhage attack was typical: with a burst of biliary colic, blood pressure came down, a list of symptoms followed: pale face, anemia, shock, and repeated attacks. Conservative treatment failed, so after one day's observation and measures, I decisively transferred this case to the county hospital to perform the proper hepatic artery ligation and external drainage of common bile duct.  The operation was a success. This entire procedure is very typical based on classical operation theory: the hepatic artery tremor was felt during the operation, which showed bleeding.  After ligation, the tremor disappeared immediately, and the common bile duct hemorrhage was delayed and stopped (as noted in the literature). Life was finally saved. This was an absolute "miracle" for the surgical level of a county hospital at that time, and I was pioneering frontier of surgery. 

At that time, our monthly salary was less than 50 yuan.  This case cost more than 1,000 yuan in the entire treatment,  so he was nicknamed as "1,000 yuan".  How can a poor farmer afford this astronomical amount of money?   Fortunately, in the era of Mao's "curing the wounded and saving the dying", the poor lower middle peasants’ medical charges could be simply written off following some logistics, which has been passed from mouth to mouth with approbation in the society. 

Another example is the splenic rupture at Donghe. My colleague and I were called for the urgent house visit.  We performed splenectomy successfully on the spot on a desk of the commune.  The wonder in this case was our use of 800ml abdominal blood for self-transfusion to overcome the problem of no blood source. 

Although it is defibrinated blood, it is without anticoagulation, yet it does not need to be anti-coagulated (thereby solving another difficult problem of no anticoagulants on hand) as it is the self-blood on the spot.  This was a first bold attempt forced out by the emergency in innovation.  Life was saved.  The road paved out, as it is so-called "the times make heroes”.   This innovative practice was later supported and theoretically recognized by the surgery community.  Its efficacy report gradually appeared as legit rescue in the literature. 

There was a difficult labour case at Xinlin, in Fanchang, with intrauterine transverse position of fetus and uterine aura rupture, too critical to transport to county hospital.  Cesarean section had to be performed on the spot.  An office desk was used as the operating table, a cloth was pulled on the top to block the ash, with disinfectant sprinkled on the ground, I performed the operation with an infusion under local anesthesia, which saved two lives.

3.  Surgical practice during special period of “civil fighting”

During the Cultural Revolution, there was a special period of chaos when the various factions were armed fighting with real fire arms.  Traffic was interrupted, and hospitals were shut down.  Bullets had no eyes, and gunshot wounds ensued.   They had to be operated on the spot to repair the damaged liver and lungs, kidney, intestines and stomach, etc.  At that critical period, I was forced to take the challenge of practicing these urgent surgeries for rescue, like in a war.  Many lives were saved and most of the cases were successful.  It was a special war-like time, so in case of accidents during operations, there was no strict accountability check.  It was also a unique period when my surgery skills advanced rapidly with tons of urgent surgery practice demanded then.  Indeed, practice generates expertise.  

This is an era of serving the people, and all this will not bring economic benefits, nor will we pursue benefits at that time. 

4.  AS guest surgeoN

After joining Wuhu Changhang Hospital in August, 1985, this affiliated staff hospital did not demand a full work load, so I had some extra time to serve as a guest surgeon for other hospitals. 

4.1 I served as surgical consultant for Xinwu District Hospital for three years, until the hospital was restructured and turned private.   Every Saturday morning, I administered an expert clinic.  I was also responsible for managing the patients’ ward.   During that period, all surgical operations were conducted by me, and for almost all daily operations I would be present. Mr Chen, the president of this hospital, suffered from gallstones, and I performed the operation right there in the hospital. 

4.2  The Municipal Tuberculosis Hospital, later named as Municipal Red Cross Hospital (Sixth Hospital), is located in  suburban Yueya Road. This hospital is also responsible for some comprehensive medical treatment for the people in its neighborhood.  However, this is a specialized hospital, and the surgery expertise is zero.  The hospital leader came to me and asked me to take over the surgical work in this hospital. I was at the time also with "excess energy", so I organized a queue of surgical directors of various hospitals from all districts and factories in the city, and requested the director of radiology department of our hospital to be the chief shift supervisor (equivalent to the chief resident).  The day shift and night shift watchmen came from 4 or 5 hospitals.  Where there was a need for operation, I would take my anesthesiologist, Mr. Chen, together with me to the hospital in the hospital car.  In this way, in more than a year, we performed hundreds of operations, involving various areas of surgery, gynecology, orthopedics and urology, related to stomach, gallbladder, appendix, lumbar intervertebral disc, uterus, fracture, etc.  Meanwhile a number of surgical new talents were also trained there.  During this period, a rare case of pyometra was encountered.  In order to clear the focus at one time, hysterectomy was performed for the first stage, and the recovery was smooth.  That was also the first such operation in this hospital. 

4.3 For No 4 Hospital and Municipal Psychiatric Hospital, surgery, orthopaedics, obstetrics and gynecology are not their forte, and there was a lack of related talents.  However, as a hospital, their comprehensive medical care is still indispensable.  Therefore, when they encountered problems in these area, I was the support they relied on.  From time to time, I went on visits to have performed cesarean section, choledocholithiasis and other operations for this hospital. 

4.4  Matang District Hospital, located in the south of the city, is a connecting part of urban and rural areas.  Although it is a class 2 hospital, there is insufficient technical strength and it often calls for diagnosis guidance.  With my anesthesiologist, I served for their surgery emergency rescue.  One case with acute suppurative obstructive cholangitis was treated right there by an emergency operation successfully . 

4.5.  Zheshan Branch, Jiangdongchang Hospital, is a class one hospital in the city, close to Hongmei New Village where I live.  So it is convenient for me to be called for help any time. Basically, I took care of all the surgical matters there, which lasted for many years.  It's my “backyard”, sort of.  Although they all have deputy chief physicians, they still lack the experience and ability to support all the comprehensive surgeries needed independently.  It's a "win-win" and mutually beneficial for me to support them on call.  When my hometown acquaintances and old patients turned to me for treatment, for convenience and economy, I could solve most of their problems there. Hence I have done a lot of operations on the spot.  

My child’s fifth uncle had rectum cancer and came from Hefei to me for help.  I had a radical operation on him in Zheshan.  It took him 7 hours to get through this critical stage because of massive bleeding before sacrum.  He was cured 

A case of thoracic vertebra fracture with high paraplegia from Nanling had my operation of spinal canal exploration and decompression in Zheshan too. I also performed a caesarean section for a doctor in this hospital,.  I also demonstrated vaginal hysterectomy for the training of the surgeons there. 

A large number of routine operations are performed there, often dozens of surgeries in one month.

5. Numerous weekend house calls 

Over time, I have become their perennial consultant in numerous hospitals such as Sanli, Yijiang (the second and third branch hospitals of Nanling), Family Planning Station, Schistosomiasis Station, Hewan, Xuzhen, Chengguan.  Almost every weekend, I was on my way back and forth to help with their operations. 

Lumbar disc herniation and lumbar spinal stenosis are common diseases in orthopedics, which belong to the Level -3 and Level-4 operation of high difficulty.  My confidence in performing such surgeries comes from my many years of clinical experience and my studying orthopedics under Professor Jingbin Xu, the top orthopedic master in China.  Not long before my own serious illness and operation in 2007, I drove out in the morning to Nanling schistosomiasis control station, and performed the operation on three cases within one day.  The key to ensure success is to completely loosen the compressed nerve root and spinal meningeal sac.  The curative effect is then definitive.  That afternoon after three surgeries performed, it was still not too late for me to drive home for dinner.  

There is another case of Wang XX, a young driver and also a family friend of mine, who also suffers from this disease.   She is restless day and night, and cannot move.  Dr. Lin, the president of the Second Hospital of our city (who is my junior fellow), and I performed an operation on him in Zheshan Hospital.  After decompression of the vertebral lamina, he was able to drive a car again three months after the operation.  For more than ten years now, he has had no symptoms and has enjoyed normal activity in work and life.  He has made himself a billionaire today. 

6. Save the performance at operation table any time 

6.1.  Once in a private hospital of Guniushan, Nanling,  they had a surgery on-going but could not find the expected bilateral ureteral stones during the operation.  Their dean gave me an urgent call for rescue and he was waiting outside on the parkway.  I immediately took a taxi, and in less than an hour, I went on the operation table, taking out the bilateral stones and smoothing the urine flow to have saved the surgery. 

6.2. Once there was an urgent case of subacute perforated peritonitis of a transverse colon cancer in Yijiang Hospital.  At three o'clock in the midnight, they called for my help.  I had to get up to rush for a taxi.  It also took me one hour to get onto the operation table, and I stepped down at dawn with the first stage excision and radical cure of the lesion.  It has achieved long-term curative effect, saving the patient as well as the doctor initiating this surgery.  In fact, they are all my disciples and trainees in the past.  Of course, I feel the responsibilities to be on call to help them any time needed, without hesitation.

7.  Tangshan  Earthquake 

In the July 28, 1976 Tangshan Earthquake, the official death toll was 240,000.  On August 3rd, I was called to go to Tangshan for earthquake-related medical treatment and rescue.  Before getting on the bus in Wuhu, the central authorities gave us a telex: the wounded are being transferred to the south so we do not need to go northfor their treatment.  As the appointed team leader, I organized a medical team of 25 people from Fanchang, Jingxian, Nanling counties plus 25 additional logistics security guards.  The task given to me was to receive and treat 100 wounded people.   Of course, all expenses are covered by the state. It is ordered as a serious political task for us to accomplish.  We set up a temporary treatment site beside the railway at a small town Eqiao. Then I led the team to the Nanjing station in a specially assigned emergency train to take over the patients in orthopedics. About three months after our treatment and care, we had completed this glorious task and sent all of them back to their hometown safely.  It is a historical monument. 

Most of these patients involved fractures, peripheral nerve injuries and spinal cord injuries with paraplegia.  There were not many operations, most of the treatments are of rehabilitation.  This large-scale urgent medical activity involves dozens of sites like ours in Wuhu area, whose leaders include authorities of orthopedics like Jingbin Xu, director of the 127 Hospital of the People's Liberation Army, and Naiyi Chou, director of the former Yijishan Hospital (the medical captain who led medical teams to South Yemen twice).   We medical team leaders meet regularly and discuss all clinical problems and measures.  I am both the captain and the backbone of orthopedics, having participated in the entire process of this rare undertaking. 

8.  Remote consultation and diagnosis 

During an online chat,  my son Wei in the U.S  said that he had severe "heartburn" from time to time, as he said, “it comes and goes, but when it strikes, it is unbearable.” His family physician asked him to have a gastroscope and checked his heart, but he never thought he was suffering from biliary colic.   A healthy middle-aged man, with sporadic pains striking and leaving, what could have been the cause?  On this side of the ocean thousands of miles away from him, I remembered that he had mentioned one year earlier that his annual physical exam found gallstones but it was asymptomatic then.  It must be biliary colic kicking in!  But he didn't agree with my suggestion. He was convinced that it had nothing to do with gallstones because the pain was from the heart area.  I am professionally sensitive and experienced, insisting on my diagnosis: this is gallstone colic, and it can be cured by surgery.  He then followed my advice to see his doctor again, reminded him of this possibility, and then had an ultrasonic examination, coming back with a definite diagnosis.  A laparoscopic operation was performed, and it cured him instantly.  He has been amazed by this experience of my remote diagnosis and has enjoyed a healthy life since.

There have been many similar incidents.  One day, our head nurse called me and said that her husband suddenly had severe abdominal pain.  I knew that he had a history of bleeding from gastric ulcer, so I naturally thought that it must be related to perforation complicated with peritonitis.  I told him to go to the hospital immediately and make preoperative preparations, such as taking an abdominal fluoroscopy, checking blood, etc.  At the same time, I went to the emergency department.  Although no "gas layer" was found under the diaphragm, I still went on with a decisive surgery and managed to perform radical gastrectomy for him.  It is more than ten years now, and he has enjoyed a healthy life.

Many of my out-of-hospital practice and visiting operations, and my being so interdisciplinary in medicine, are the special products of my era.  According to today's standards of high specialization, such practice is neither standardized nor rigorous.  Nevertheless, my special skillset has managed to save many lives and cured many diseases.  It is an indelible mark in the career of my medical practice, demonstrating a significant contribution to society. It has made a difference to my patients and hard for them to forget.  In my life, I have had countless sleepless nights, with eating and sleeping in total disorder, but the sense of self-satisfaction in saving lives is more than enough to comfort me with deep pride and joy.   Nothing could have been better, I have no regrets!

More recently, with the rapid development of science and technology, medicine is also making great strides, evolving with each passing day.  In the ascendant, medical instruments and drugs also see revolutionary development, especially striking to me are the new drugs and the orthopedic equipments, such as stapler, occluder and repair mesh, etc.  As I have been on duty all the time, I feel extremely fortunate to have got on this "last bus", although most peers in my generation are now blocked at the door.  However, the currently popular techniques like laparoscopy surgery, minimally invasive technology is still a blind spot for me, due to the equipment requirements beyond my reach. 

In recent years, a large number of new concepts and terms have appeared in medicine, such as translational medicine (TM), targeted therapy (TT), evidence-based medicine (EBM), etc. I keep up with the times, continuously update my knowledge and keep on following up.  Both in theory and clinical practice have been undergoing changes. 

According to the requirements of fine division of labor in modern clinical medicine, in the past five years after my own gastrectomy, I have basically given up other related professional work outside general surgery, such as orthopedics, obstetrics and gynecology and even urology. This, too, is a way to help create bigger room for new talents to be superior to masters, and shows the progress of society.  My professional title is "General Surgery" chief physician, and I will stick to this area for the remaining path of my career, never fall behind in my lifetime and stay young and energetic! 

My eldest granddaughter is a senior with the 8-year medicine practitioner curriculum in Tongji Medical University, Wuhan.  She is expected to follow me to become the next doctor in my family.  Well-educated, standing from a high starting point, she came to my hospital as a trainee and intern during the Spring Festival holidays last year. When she wore a white medicine costume, she looked like a brand-new doctor in the 21st century.  This baton is passed down to her, and I feel that it is a perfect legacy carry-on for my medicine career,  there’s nothing more I could have asked for.  Admittedly, this profession calls for enduring dedication, involving huge risks and hard work.  However, it also provides a platform where the value of life is most experienced and demonstrated!

October 2011

 

《李家大院》7: 我的外科生涯—-院外集锦

【李名杰从医66年论文专辑(英语电子版)】

Debriefing report

In support of Application for Chief Surgeon

Since the resumption of professional journals and academic activities after the Cultural Revolution in 1979, I have published dozens of papers in journals such as Southern Anhui Medicine, Journal of Bengbu Medical College, Lectures of Provincial Medicine, Domestic Medicine (Surgery) and Jiaotong Medicine.  In 1979 and 1980, I participated in the preparation and re-founding of Anhui Orthopedic Society and Surgical Society respectively, and attended the annual meetings (1-6 sessions) of the two societies.  I also participated in many academic activities of surgery in China and the Ministry of Transportation.  

In 1994, I was involved in the planning and organization of a symposium on orthopedics in the Yangtze River Basin area, helping to compile a special issue of Orthopedic Clinic for Journal of Southern Anhui Medical College, Vol-13 supplement, 1994) under the guidance of Professor Jingbin Xu, editor of Chinese Journal of Orthopedics, carrying over 100 published papers, with participants and contributions from all over the country.

In September, 1995, I published two papers at the National Academic Conference on Acute and Severe Surgery (Guilin, 1995), among which "Problems in the Treatment of Liver Trauma" (0190) won the certificate of excellent papers.  I have also published papers in the First International Academic Conference of Chinese Naturopathy (Chengdu, 1991) and Naturopathy (published in Taiwan Province).

1 Professional path and deputy chief physician performance

 (On evolution of several theoretical problems in surgery)

1.1 In the early 1960s, a large number of patients suffered from acute volvulus, ascaris lumbricoides intestinal obstruction and cholelithiasis.  Carrying out a large number of related operations for these cases consolidated my mastering  the basic surgical skills.  In addition, for the treatment of toxic shock in late cases, we practitioners underwent an arduous zigzag path from vasoconstriction and pressure increase to volume expansion and improvement of microcirculation, which proves to be an epoch-making change and progress both theoretically and clinically. 

1.2  In Southern Anhui, there used to be a large number of patients with portal hypertension, hypersplenism and upper gastrointestinal bleeding in the early years of late-stage schistosomiasis and late hepatitis cirrhosis. techniques. The medicine community has also gone through a process of repeated debate and re-evaluation of the choice between shunt and devascularization techniques.  In this regard, as far back as in 1975, I performed splenectomy, splenorenal vein anastomosis and other types of shunt surgeries. Due to the high rate of postoperative embolism, the blood supply to the liver was reduced and hepatic encephalopathy was easily induced.  Later on, I switched to various types of portal-azygous devascularization, and obtained many lessons and various experiences for improvements from the treatment of this difficult problem. 

1.3 Biliary lithiasis still bothers the surgical community. With the development of hepatobiliary surgery and improvement of monitoring methods, surgical procedures for this challenging problem of intrahepatic calculi are constantly updated and improved.  I started the surgery of regular resection of the left lateral lobe of the liver for this disease in 1980 (the paper on five early cases was published in the Annual Meeting of the Provincial Surgery in 1980 and in Journal of Southern Anhui Medicine (80, 13; 51, “Regular resection of the left outer lobe of the liver for the treatment of intrahepatic stones”).  Also starting in 1980, various types of choledocho-intestinal drainage (Finster, Longmire, Roux-en-Y, etc.) were successively performed.  In 1992 and 1995, three cases were treated with intrahepatic bile duct incision, stone removal and plasty, and "basin" biliary and intestinal drainage (The first case was reported in “Communication Medicine”,  93,7; 91, “A case of hepatobiliary basin type biliary enteric drainage”). This work advanced the operation to the treatment of intrahepatic lesions, leading to improved  clinical efficacy. 

1.4 In recent years, the incidence rate of acute pancreatitis has increased. All severe pancreatitis patients in my department were cured by measures such as focus removal, pancreatic bed drainage, intraperitoneal lavage, 5-Fu, somatostatin and other measures to inhibit exocrine, anti-shock and anti-infection. In recent years, one patient was rescued in my department despite the complicated stress ulcer bleeding after operation was performed in another external hospital.  

1.5 On the basis of treatment and operation for various thyroid diseases, hyperthyroidism operation was performed after 1980, and two cases of radical thyroidectomy (neck-mimicking surgery) were performed in 1994. One case was re-operated due to recurrence 3 years after the initial surgery was performed in an external hospital.  No further recurrence was observed during follow-up.  

1.6 In addition, there are surgeries such as excision and anastomosis of cervical aneurysm, thymopharyngeal duct cyst, thyroglossal duct cyst and cystic hygroma resection, etc. 

1.7 Over the past 30 years, more than 1,000 cases of breast cancer, gastric cancer, colon cancer and rectal cancer have been treated, and many of them have survived for a long time.   

1.8  The prevention and treatment of short bowel syndrome after large intestinal resection as a surgical method of interposition of distal reverse peristaltic bowel loops, the observation shows no diarrhea and malnutrition for 21 years. This paper was published in the Journal of Bengbu Medical College (82; 7: 214, PEUTZ Syndrome) and Traffic Medicine (91; 1: 41, “Surgical treatment of short bowel syndrome”).   

1.9 The management of duodenal injury has its particularity and complexity, and its retroperitoneal injury is especially prone to missed diagnosis and misdiagnosis.  The prognosis of patients who underwent surgery more than 24 hours after injury is grim.  In a case report from 1994, following the principle of "rest transformation" of duodenum, I performed a Berne-like operation 28 hours after injury, and the recovery was smooth. My paper was published in Communication Medicine (“Experience in Diagnosis and Treatment of Closed Retroperitoneal Duodenal Injury”, by Mingjie Li). 

1.10  Subdiaphragmatic total gastrectomy, jejunostomy, supradiaphragmatic esophagectomy, thoracic esophagogastrostomy, lobectomy, mediastinal thymoma removal, diaphragmatic hernia repair, etc. which started years ago.

2. Work involving various medicine disciplines 

The two hospitals I have served are both base-level primary hospitals. The "major surgery" department covers general surgery, orthopedics, urology, chest surgery, obstetrics and gynecology, ophthalmology and otorhinolaryngology,  anesthesia, radiation, laboratory test and other related work.  As professional subject leader, I have long been engaged in the work of all of the above areas, outlined below. 

2.1 Orthopedics is one of my key areas, only second to general surgery.  I have performed all major surgeries in this area, and participated in academic activities at all levels, including publication of numerous papers, professional talks and compilation of a special issue on Orthopedics.  My representative operations treating bone injury and bone disease include closed nailing of femoral neck (for the paper, see Orthopedics Clinical 1994, 13:37, Closed nailing treatment of femoral neck fracture in 45 cases), surgical paraplegia (paper in Anhui Province Medical Lectures 1982;, 4:21, Surgical paraplegia analysis of 14 cases), spinal tuberculosis surgery (paper Spinal tuberculosis a surgical therapy in Proceedings of First Provincial Orthopedic Annual Conference, 1979), lumbar disc surgery, spinal cord tumor enucleation, bone tumor removal and orthopedic surgery, etc.    

2.2 Urological surgery: nephrectomy, stripping of renal pedicle lymph nodes, removal of various segments of ureteral calculi and Urethral trauma realignment repair, ureteral transplantation, vasovasostomy, spermatic vein–inferior epigastric vein anastomosis, hypospadias repair, radical resection of bladder cancer and penile cancer, etc. 

2.3 Gynaecology and obstetrics: I founded the department of obstetrics and gynecology of our hospital, having operated Cesarean section (lower segment and extraperitoneal operation), hysterectomy (abdominal type and vaginal type), oophorectomy, repair of vesicovaginal fistula and cervical cancer resection, etc. 

2.4 Ophthalmology and otorhinolaryngolog: parotid gland, tonsil, maxillary sinus, mastoid, cataract, artificial pupil, enucleation, nasolacrimal duct anastomosis, strabismus correction, etc.   

2.5 Anesthesiology: various segments of epidural block, cervical plexus block, brachial plexus block, intubation general anesthesia and intravenous compound anesthesia, etc.    

2.6 Radiology: I founded the department of radiology in 1960, and concurrently served as the head of the department for 2 years (1960-1962).  Very familiar with its routine work and related angiography. 

Environment trains people.  A wide range of issues encountered in the long-term work of grass-roots hospitals enabled me to dabble in many subjects.  The knowledge and skills of these relevant areas complement each other, contributing to and deepening the improvement of my surgical expertise.  Various Level-4 and Level-5 surgeries have been performed to keep placing me at the forefront of contemporary surgery.

3  Continuous innovations and some experience to share 

Over the past 40 years, with high technological development, diagnosis and monitoring methods are constantly updated.  With the change of social life, diseases are also changing. In an aging society, geriatrics takes a prominent position.  Many factors make the clinical work evolve too.  This requires physicians to constantly hunt for scientific and technological information, learn from the experience of others, study hard and embrace the courage for innovation, in order to improve the service quality for our patients. 

3.1 Improvement and innovation 

3.1.1 The key to the control of traumatic infection is complete debridement at the first diagnosis, rather than relying on drainage and antibiotics.  Techniques involve a large quantity of water washing, elimination of foreign objects and inactivating tissues, disinfection, and no suture.  When postoperative inflammatory reaction occurs, apply local wet compress with alcohol, supplemented with with or without antibiotics.  Following this strategy, surgery within 6 hours of trauma is almost completely free from infection. 

3.1.2 Over the past 30 years, based on the experience of over 1,000 cases of gastrectomy I have performed, the preset gastric tube has basically been abandoned except for special needs, and there were no cases of failure.  This requires excellent anastomosis, perfect hemostasis, intraoperative emptying of the residual stomach, and attentive postoperative monitoring. 

3.1.3 For extensive peritonitis, after the nidus and infectious substances are removed, abdominal cavity drainage can be abandoned to reduce postoperative adhesion.  The key for this to work is to wash it thoroughly during the operation.  As the drainage is quickly blocked by fibrin glue in the abdominal cavity and soon stops working, it only increases the pain of the patient. To be sure, however, in cases such as pancreatitis, abdominal abscess, etc., if continuous overflow is expected, double-cannula negative pressure drainage is still required.   

3.1.4  For any surgery, regardless of scale, its success or failure makes a big difference to the health and safety of patients.  As a surgery practitioner, I attach importance to the technical improvement of each and every "small" surgery.  Some of my technical innovations and experience are outlined below. 

For inguinal hernia repair, the focus is the transverse abdominal fascia, the traditional Bassini method should be replaced by the modified Madden procedure, which greatly reduces the pain of postoperative tension suture for patients, and is also conducive to healing, with the recurrence rate  greatly reduced. 

For circumcision, the conventional routine procedure has plagued both doctors and patients with the poor alignment of the inner and outer plates, hematoma, edema, as well as difficulty in stitches removal.  I modified the procedure, using local venous anesthesia to support neat cutting under a tourniquet, with perfect hemostasis, accompanied by careful sutures with human hair or absorbable thread.  The benefits include no pains during the operation, good alignment, fast healing and avoiding stitches. (see my paper published in Jiaotong Medicine 90; 43)66,  Several improvements of circumcision 

Anal fistula seton therapy or open resection can cause patients to suffer from postoperative pain and a prolonged recovery period post-surgery. I used long-acting anesthesia (with local injection of diluted methylene blue) to ensure the primary resection and suture. Most cases receiving this treatment result in primary healing, with the course of treatment greatly shortened.

3.2 Some General Experiences 

Based on what I have learned from my 40 years of hands-on surgical practice, I feel that in order to be a qualified surgeon, we need not only consolidate the basic knowledge with continuous updating, but also exercise meticulous working methods with a high sense of responsibility, supported by logical thinking and practical orderly working style.  It is very difficult to just follow a unified norm or standard procedure when the real-world surgery scenario involves so many moving parts to be weighed and considered, factors like the ever-changing condition, physical differences, positive and negative effects of drugs, advantages and disadvantages of the techniques in consideration, the reserve function of body organs, the length of the course of the disease, and even the natural environment, mental and material conditions, and so on.  One must be equipped with high adaptation wisdom.  It is not an exaggeration to say that the adaptation ability determines a surgeon’s diagnosis and treatment level and the clinical effects.   

3.2.1 The entire process on the operating table involves struggles between personal fame and the interests of patients.  The so-called following "safety first, and draw the line accordingly” principle is often not a feasible practice.  A competent physician must have the courage to take risks for his patients. It is often the case to be placed in the position in fighting for patients' good chances of rescue that can be missed because of a small mistake in one's thinking.  I have countless memories of such incidents in the past, one of which is as follows.  In the fifth operation of biliary tract, cavernous blood vessels caused by portal hypertension due to biliary cirrhosis were distributed all over the hepatic hilus, and in addition, the inflammation was thickened.  After struggling for 8 full hours of operation, I finally managed to open the biliary duct and save the life of the patient.  This was a victory of perseverance. 

3.2.2  Adjust measures to real world conditions, and keep an open mind to break the routine to save a patient.  The key to life-saving in case of liver and spleen trauma and massive hemorrhage of ectopic pregnancy in the countryside lies in rigorous transfusion of the abdominal blood.  To wait for the blood supply in these scenarios means to wait for death.  I remember a case of liver trauma in which 1700ml of liver blood was transfused locally to support the successful operation.  (See paper Related issues in the treatment of liver trauma (review), in Proceedings of the National Academic Conference on Acute and Major Surgery, 95; 190 

3.2.3 For difficult surgery and new surgery, one must accumulate the relevant knowledge and operation skills, by reviewing literature, consulting experienced experts for guidance, and visiting and studying surgery scenes, before embarking on the operation, to minimize potential misses or accidents.  In my first case of hepatobiliary-pelvic internal drainage operation, I asked for direct guidance from a professor of surgery. The subsequent two cases were successfully completed all by myself.   

Looking back on my 40 years of career in surgery, I deeply feel that clinical surgery is a combination of science, perseverance, determination, and a sense of responsibility.  It is like a small boat that ups and downs in the forefront of the waves.  Walking on thin ice, one can hit hidden rocks at any time.  The hardships and risks of our career are among the highest in all trades.  Fortunately, I have not failed the society.   Along the journey, there have been countless joys of success, together with many sleepless nights and panic moments.  For the rest of my career years, I am determined to maintain the service spirit of "healing the wounded and rescuing the dying", to complete the journey to the end.   

 

Appendix 1, Publications
Appendix 2, Relevant Materials and Records of Level III and Level IV surgeries

 

《李家大院》6: 业务自传和工作报告

【李名杰从医66年论文专辑(英语电子版)】

      

My career as surgeon

Before writing my debriefing report in support of my application for Chief Surgeon, let me start with three unforgettable orthopedic cases that I experienced in my medical practice. 

In 1970, my old schoolmate and close friend from junior high school, Mr. Gui from Fanchang No.1 Middle School at that time, brought his son’s case to my attention.  His son, aged 16 then, suffered from cervical vertebra 5 tuberculosis with cold abscess, which severely oppressed esophagus and trachea. He was unable to eat, and had difficulty breathing, with hoarseness, dehydration and hypoxia, in a critical condition.  

They had visited Yijishan Hospital, the largest hospital in Wuhu, but the director there Dr. Chen of the Department of Orthopaedics could not admit this case, saying that a few days before, a similar case, died during the operation.  He made the suggestion for the patient to be sent to the provincial Hospital of Hefei, which required 800 yuan then.   However, Mr. Gui’s monthly salary was only 52 yuan, and he had to support a family of six with this income.  How could he afford it?  Besides, nobody knows whether the chief hospital in Hefei could treat him.  In a hurry, Mr. Gui turned to the No. 127 Army’s Hospital located in the suburb of my town Nanling, to try their luck there.  The corresponding department of the hospital was administered by Dr. Xu Jingbin, the nation-wide orthopedic authority, and this military hospital located in a small place long had a tradition of helping the poor.  Unfortunately, Dr. Xu was on a business trip to Nanjing, and several of his subordinates there were too afraid to accept this high-risk patient.   

Feeling helpless, Mr. Gui came to me in Nanling County Hospital (the two hospitals are only 5 miles apart) to discuss possible rescue plans with me.  I was not sure about how best to treat this condition either.  However, I had studied in No. 127 Hospital, with Dr. Xu as my supervisor, familiar with the personnel there.  I immediately called an ambulance. We went back to No.127 Hospital, found doctors in orthopedics and surgery, and asked them to work together for the treatment of this urgent case.  Mr. Gui as patient’s family and I jointly signed the required paper for willing to take the risk of the operation, and discussed the detailed rules.  However, this plan was still not approved by the hospital.  Instead, the hospital asked me to help them out of this embarrassing predicament, and promised a free car to be used for transferring the patient to big city hospitals in Hefei or Nanjing.  The patient's life was in danger at any time. Far water cannot put out the near fire, so it's not advisable to transfer to hospital far away. 

I decided to take on the challenge myself.  At that time, I thought, at least I could give pus discharge for saving life first, relieving the oppression of esophagus and trachea, and making it possible for hime to eat and breathe.  So the patient was brought back to the county hospital where I worked.  Without even getting off the stretcher, I ordered to first give fluid replacement and antituberculosis.  At this point in the evening, Mr. Gui didn't get any food for a whole day, so he was given dinner at my home.  I could not afford the time to have a dinner.  I took the time to review the related literature and anatomy.  Half an hour later, the patient was sent to the operating room under local anesthesia. After my careful dissection, the patient’s pus cavity was cut to release a large amount of pus.  The patient immediately started making sounds, could sip the water, and breath smoothly, indicating him finally put out of immediate danger. 

The operation continued, exposing the focus of cervical vertebra 5 by anterior approach, I removed the dead bone, scraped off the granulation of tuberculosis, flushed the pus cavity, inserted streptomycin and isoniazid, put the drainage piece in, with suture.  The operation was smooth and very effective.  The fever came down 3 days after operation.  The patient went to get a haircut, ate normally and recovered well. 12 days after the operation, he was discharged from hospital, and his medical expenses were 32 yuan.  He continued anti-tuberculosis treatment for half a year and recovered well.  For more than 40 years now, the patient has been working and living normally, now enjoying a family of his numerous children and grandchildren. 

In addition to the complicated anatomy of the neck, such as dense blood vessels, nerves, thyroid gland, trachea, esophagus, etc., this type of cervical tuberculosis debridement operation is of high difficulty also due to the fragility of the cervical spine and the destruction of tuberculosis.  If there is a slight mistake in the cervical spinal cord, it will lead to being paraplegic at a high level or even death.  It's an orthopedic high risk level 4 operation.  Even in big hospitals, the directors are extremely cautious in treating such cases.  I was still a newcomer in orthopaedics then, but I needed to save lives, knowing that transferring to another hospital at that time was basically a dead end.  The patient was on the verge of an abyss.  But I also had some of my own strength and preparedness for this success.  I had had many years of experience in neck thyroid surgery, familiar with anatomy, and had accumulated specialized knowledge in orthopedics.  This solid foundation finally enabled me successfully complete this rare problem in a grass-roots hospital.  Life threatening symptoms were treated by relieving oppression immediately.  And the disease was cured, with the lesion eradicated.  It proved to be a cure for life.  

Another case, at the end of 1980s, named Xiao Wei, a 14-year-old junior student in Wuhu No.1 Middle School, suffered from right humeral neck tumor.  He had undergone two operations in Yijishan Hospital and Shanghai Zhongshan Hospital respectively.  Now, the disease struck at the right scapula.  The director of orthopaedics in a hospital of our city said, it is malignant tumor recurring and metastasizing, amputation is necessary, and it is challenging to save his life!   The family was in a desperate situation.  The patient’s grandfather, Mr. Wu, was my junior middle school teacher.    Mr.  Wu knew about the case of cervical tuberculosis treated  well by me on Mr. Gui’s son, so he came to me for consultation.  I carefully examined the medical records and the X-ray films before and after, and diagnosed it as a new critical tumor, neither a recurrence nor a metastasis of the original disease.  I personally performed a half-excision of the right scapula in my own hospital, resulting in his full recovery.   More than 20 years have passed, and Xiao Wei has enjoyed good health ever since.  He has become a Dr. Yang in the west later on, and is now a high-end international talent in his field.  From time to time, he and his father still come to visit me with appreciation. 

The third case, in the fall of 1975, a 35-year-old female patient, who had lost 40 kilograms, was admitted to our hospital for tuberculosis of thoracic vertebrae 6 and 7 with paraplegia.  Under general anesthesia, through the chest, the focus was cleared, and the dead bone and the necrotic intervertebral disc were removed.  The tubercle granulation in the spinal canal was 8cm long, which pressed the thoracic spinal cord, resulting in spinal canal obstruction and paraplegia.  After curettage, it could be seen that this segment of spinal cord was throbbing again.  The focus area was thoroughly washed, with antituberculosis drugs added in.     The ribs cut during thoracotomy were trimmed and embedded in the intervertebral defect area, and the anterior bone graft was completed in one single stage. After operation, the patient recovered well and was cured.  The patient’s husband was a blacksmith, who gifted me with  a stainless steel kitchen knife and a spatula of his own craftsmanship, which are still in use in my home today.  In orthopedic surgery, this belongs to the top level-four category.  With thoracic tuberculosis complicated with paraplegia, the cure was one-time lesion clearance and bone grafting through the anterior thoracic approach, definitely having reached the peak in county-level hospitals. 

Such cases have brought me a great sense of pride and accomplishment, and they form the motivation for my lifelong dedication to saving lives and relieving pains for my countless patients.

 

【李名杰从医66年论文专辑(英语电子版)】

       

【李名杰从医67年论文专辑(英语电子版)】

COLLECTED WORKS IN COMMEMORATION OF MINGJIE LI'S 67 YEARS OF MEDICAL PRACTICE

 

© Mingjie Li

Dr. Mingjie Li has been practicing medicine for over 60 years. This collection, compiled to commemorate his amazing career, includes three sections: (i) career memoirs, (ii) medicine papers, and (iii) medicine education. The publication of his medicine papers is the culmination of his extensive experience and expertise in the field. His work has been recognized by his peers for its professional value and rigorous style. In addition to surgery, orthopedics, obstetrics, and gynecology, his work at times also incorporates elements of traditional Chinese medicine. The "Operation Records" section in the appendix provides detailed descriptions of operation procedures and emergency measures, making it a valuable reference for professionals in the field. The "Education Section" highlights Dr. Li's practical experiences and medical training materials he compiled, providing valuable insights into a range of clinical topics. Overall, this collection serves as a testament to Dr. Li's impressive career and contributions to the field of medicine."

August 2023, Wuhu, Anhui, China

 

 

Table of content

 

The Tireless Father (Preface)

I: Career memoirs

My career as surgeon

Debriefing report

Service beyond my hospital

Career Path and self review

Dad’s medical career (by Wei Li)

II: Medicine papers

Regular resection of left lateral lobe of liver for intrahepatic calculi

PEUTZ syndrome

Surgical management study of hepatic injury

Surgical treatment of acute gastroduodenal perforation

Diagnosis and treatment of closed retroperitoneal duodenal injury

Surgical treatment of short bowel syndrome

Hepatobiliary basin-type biliary-enteric drainage

Biliary enteric drainage

Several special problems in diagnosis and treatment of biliary tract surgery

Diagnosis and treatment of close duodenal retroperitoneal injury 

Misdiagnosis of subacute perforated peritonitis in gastric malignant lymphoma

Adult retroperitoneal teratoma infection complicated with chronic purulent fistula

Ingested lighter as a foreign body in the stomach 

Successful primary repair of congenital omphalocele

Recurrent stones in common bile duct with suture as core

A case of plastic tube foreign body in bladder

Abdominal trauma

Subcutaneous heterotopic pancreas of abdominal wall

Several improvement measures of circumcision

Clinical observation of a new minimally invasive circumcision

A surgical treatment of spinal tuberculosis

Transpedicular tuberculosis complicated with paraplegia

Surgical analysis of surgical paraplegia

Lipoma under soft spinal membrane complicated with high paraplegia

Treatment of femoral neck fracture with closed nailing

Fifth metatarsal fracture caused by varus sprain

Intervertebral disc excision in community health centers

In commemoration of the 50th anniversary of Dr. Xu Jingbin’ s medical career

Intrauterine abortion combined with tubal pregnancy rupture

Rivanol induction of labour by amnion cavity injection

Extraperitoneal cesarean section

Prevention and treatment of trichomonas vaginalis and mold infection

Non-operative treatment of senile cholelithiasis with integrated traditional chinese medicine

Treatment of acute soft tissue injury with moxibustion

Treatment of scapulohumeral periarthritis with acupuncture combined with warm moxibustion

IV: Medicine education

Level 4 Surgery

New concept of modern surgical blood transfusion

Extrahepatic biliary injuries

Surgical treatment of thyroid cancer 

Indications of splenectomy and effects on body after splenectomy (DRAFT)

Treatment of carcinoma of pancreas head  and carcinoma of ampulla (DRAFT)

Treatment of cardiac cancer

Treatment of recurrent ulcer after subtotal gastrectomy

Treatment points of radical resection of colon cancer 

Medicine Lecture Notes

The Story of My Father (An Epilogue)

 

Related Online Links

 

 

 

 

【李名杰从医67年论文专辑】(电子版)

《朝华午拾》电子版

《李家大院》电子版

《李老夫子遗墨》电子版

《小城青葱岁月》电子版

《江城记事》电子版

 

立委兄近期文章目录

语言创造简史

(见鬼,这一篇旧文居然被kexuewang屏蔽,留存 here)

屏蔽已有 4203 次阅读 2014-12-18 00:36 |个人分类:立委科普|系统分类:科研笔记| NLP, 语言, 编译, 自然语言

设计和实现一个语言是一种非常有趣的事儿,自己做上帝。说起语言王国和上帝的关系,话也长了。自然语言据说是由一群名叫约定俗成的众神团队创制的,缺乏规划,无为而治,词汇和文法的起点均具有很大的随意性,显然不是一神教说的真神所为。然而,语言是何等神器,它是交流的工具,知识的载体和合作的基础。人类一旦掌握了共同语言,齐心造反就容易了,绝不会安于伊甸园里面吃吃果子。真神于是有些怕了,决定搅乱自然语言,使得人类不能顺畅交流,内讧不断。这才有人类世代努力建造通天塔企望大同而不成。直到如今,世界仍不太平,语言依旧混乱,战争和恐怖时有发生。尽管如此,人类还是迎来了电脑革命的新时代。

以前一直不理解计算机这么些年为啥有那么多狂人前仆后继,发明了这么多不同句法和风格的语言,这不是为难人吗。说到底还是,人毕竟不是神,想制定语言王国的条条框框,又要富于表现力,修行不足也。

人类语言繁多是可以理解的,除了前面讲到的神话,也有历史的、地域的和经济的诸原因。可是计算机的硬件和底部机器指令及其背后的逻辑都是基本一致的,完全没有道理人为生出这么多语言来。至少对于高级通用语言,书同文应该是大势所趋。连电脑语言都不统一,何来世界大同?

苹果公司最近设计的mobile平台语言叫啥来着,对,Swift,据说帅呆了。其实,历史上最成功的人造语言不是 BASIC 或 Visual Basic、C 或 C++,不是 Lisp 或 Prolog,也不是 Java 或 Swift 等电脑语言,而是为人类和世界和平而创造的 Esperanto(世界语)。世界语之父柴门霍夫博士才是简约规范与丰富灵活的无与伦比的平衡大师,值得世代景仰。

有意思的是,有时候人会因为创制了一门新语言,就以为该工具针对的问题就已经解决了。人工智能历史上,Lisp 语言以及 为其量身定制的 Lisp 机曾经刮起一阵旋风。女儿最近课上接触它,为那些没完没了的括号头疼不已,我说,难道你没看到设计者的匠心?“I can sense that”,美则美矣,太过极端(大意)。

后来 Prolog 的设计和实现,成为日本五代机大跃进的主要依据。一时间极度乐观主义在日本精英阶层流行,人定胜天,似乎制作能说人话、能自主思考的智能机器指日可待了。泡沫破灭,五代机项目是完败,本来日本雄心勃勃要借助五代机项目赶超美国,做软件产业和IT的带头羊。其结果是与美国的距离更远。

不过反过来说,知道解决问题的 knowhow(窍门),可没有合适的专项语言工具来实现,也往往望洋兴叹。通用语言可以书同文,也的确可以看到书同文的大趋势,但通用语言毕竟难以照应众多领域的特殊需求,因此专项语言的创造会不断深入下去。对于很专业的问题领域,没有针对性的专项语言,解决问题往往事倍功半。比如,很难想象用通用语言可以写出有深度的自然语言的 parser 出来。

最近思考这辈子 involved in 的三次 NLP 专用语言的设计和应用,悟出来语言设计的简洁和表达力之间的某种平衡,会对利用这个语言解决问题并维护系统产生很大的影响,哪怕本质上都是相同的 formalism。设计NLP 专用语言的特殊魅力在于其元语言(meta-language)的特性:为了分析(parse)和处理自然语言,我们需要一种元语言(专用的formalism)去描述自然语言,而用元语言编写的程序,其主体是自然语言的形式化文法,本身也是一种语言,也需要被分析(parse)、编译(compile)和运行(running)。这是何等有趣的语言之塔的螺旋上升。

第一次接触是在国内,导师制定的语言标准,简洁到无语,整个语言不允许有 SPACES,虽然基本功能都有了,还是失之于陋,而且天书一样不具有可读性。然而,在上世纪80年代的软硬件的条件下,在中国相对隔绝的环境里,我的导师刘先生创造出了一整套适合MT和NLP的语言(单有绝顶智慧是不够的,主要还是他有前20年机器翻译的经验做底),亲手实现其 parser(专项语言分析器) 、 interpreter (解释器),和融合了流程控制的 runner (导师称其为语言处理的控制器),并成功应用于实用机器翻译系统的研发中,这是非常了不起的成就。高山仰止,是我对恩师一辈子的感觉。

第二次在水牛城,与瑞典工程师合作,照猫画虎,跟着欧洲施乐实验室的样子,共同创制的。表达力丰富而规范,但没有风格,也不够专项,NLP 本体要求渗透不足。

第三次是来加州以后与印度工程师合作,NLP 本体工作是做足了,语言功能强大,具有扩展性,远远超出了传统的有限状态 formalism 的框框。但该工程师偏好结构清晰,不惧繁琐,叠床架屋,离简约渐行渐远。一个简单的模式规则,也要写一大篇代码,几乎可以与老老年 COBOL 媲美了。

有了阅历之后,如果有机会重新来过,有时间从容设计,我想创制一款既简约又丰富的专项语言来,使用她会减少出错机会,增强可读性,方便 debug,而且看上去要很美很美,过一把做优秀上帝的瘾。

【相关】

看望导师刘倬先生,中国机器翻译的开山鼻祖之一

 

【科研笔记:NLP “毛毛虫” 笔记,从一维到二维】

【泥沙龙笔记:NLP 专门语言是规则系统的斧头】

 

[转载]【白硕 - 穿越乔家大院寻找“毛毛虫”】 

【置顶:立委科学网博客NLP博文一览(定期更新版)】

https://blog.sciencenet.cn/blog-362400-851882.html

上一篇:裤子设计的一些观察
下一篇:千古一问:一切目标的制定有何意义呢?

 

9  武夷山 刘洋 徐晓 文克玲 袁贤讯 鲍得海 陈辉 zdlhsh rosejump

发表评论评论 (4 个评论)

IP: 219.140.217.*   删除 回复 |赞[4]李方和   2014-12-25 09:47

由博主此文顿悟。
历史是语言创造的!由此解决了我多年的困惑。
谁掌握了话语权,谁就能还历史以公正……!

IP: 180.156.186.*   删除 回复 |赞[3]icgwang   2014-12-18 14:39

“这是何等有趣的语言之塔的螺旋上升。”——自然进化产生自然语言,机器进化产生机器语言。按照进化生成的理解更顺些,设计/实现的描述模式有点儿人想造人的感觉。房子是先造出来的还是先设计出来的?我看还是理解为先造出来的比较实在!

IP: 61.183.148.*   删除 回复 |赞[2]张能立   2014-12-18 14:10

自然语言与现代数学及科学之间的关系(之一) http://blog.sciencenet.cn/blog-39840-852034.html 。不解决 语言落后问题,其它 问题 一切 无解。

IP: 130.87.181.*   删除 回复 |赞[1]mirrorliwei   2014-12-18 09:27

别开生面。赞一个。

《小城青葱岁月》电子版(目录)

小城青葱岁月

 --------一个中小学生的文革生活记实

      汉阳一江水  著

 

 

 

目录

 

作者寄语

 

自我吹嘘(外一篇:本人自传)

(外一篇:迎着阶级斗争风雨茁壮成长)

 (外一篇:新的征途)

(外一篇:永做毛主席的红小兵)

(外一篇:青涩少年记事)

(外一篇:师弟轶事)

四人不成帮 (外一篇:建军自述)

 (外一篇:千万不要忘记阶级斗争)

 (外一篇:我的中小学学生生活)

 (外一篇:千年的铁树开了花)

 (外一篇:北风那个吹)

 (外一篇:论社会主义时期的长期性)

(外一篇: 狼狗--刘邓)

 (外二篇:对话 我对鲁迅感觉很复杂)

 (外一篇:三兄弟惊叹学大寨)

(外一篇:那小说中的情节,也能亲身感受)

 (外二篇:土布洋布 不成故事)

 (外一篇:铁姑娘金小霞)

 (外一篇:受伤的一代)

 (外二篇: 我的邻居 苦命的外婆)

(外二篇:思考  悼念我的同学戴翠萍)

(外一篇 立委小传)

(外一篇:勤工俭学)

 (外一篇:插队的日子)
(外一篇:看病两则)
真话?假话?(外一篇:家乡的老屋)
《虹南作战史》与《前夕》(外一篇:小说《小铁》抅思、提纲和思路)
咸菜(外一篇:美德和减肥)
入学历程 (外二篇:高考随想; 跳龙门)
代后记:我们和你们 (长篇政治抒情诗) (外一篇:同学联谊会记实)

 

 

 

 

 

 

大模型短视频系列:大模型压缩与白马非马

 
 
 
 
从白马非马说起
 
大家好,我是出门问问李维的数字分身,这是我的短视频频道。
 
今天我们讲一讲著名的公孙龙的“白马非马”问题。网上最近的讨论主要是从形式逻辑出发,说明这个听上去是悖论的说法,实际上是因为语词的模糊性造成,基层逻辑其实很简单。动词“非”是多义的,既可以表示等价,也可以表示属于。白马不等于马,但白马属于马。这样分开来,非常简单明了。
 
但这里我想从哲学思辨的角度并结合大模型压缩的话题,重新剖解诠释这个老命题,提供新的视角。
 
我觉得这里的“白马”不是“白色的马”的概念,而是哲学家手指指向的“那匹白马”:你看那匹哲学家马厩旁正在吃草的白马。顺便一提,白马前面有吧个定冠词,零形式。中文没有发展出定冠词,只有指示代词,并不影响哲学家那样用它,所以,哲学家的白马,我认定是映入我们眼中的那个实体。换句话说,白马是具象化的特定实体,而不是泛指所有的白颜色的马的概念,这在认知科学中叫本体,与一个个的实体想对照,是实体的抽象结果。
 
我觉得白马非马很哲学,是因为这个哲学不承认本体,只认实体。只有具体的一头头的这匹白马、那匹黑马、张家刚出生的小马、李将军的那匹战马等等,世界上哪里会有抽象的马呢?这就有意思了,这是不同的世界观。
 
这类哲学家认为,放眼望去,所见皆实体,实体才是客观世界的本质,而本体只是人类社会发展出来的主管系统,具体说,是人脑的产物或反映。人类是一种奇怪的动物,自从走出非洲森林,人脑开始发达,语言和思维卷来卷去,就卷出来这一整套本体论,叫 ontology,硬是为一片混沌的世界建立了秩序。
 
在蚂蚁的眼中,是不应该有本体这种独属于人类认知的实体幻象的,最多也不过是一种极其粗糙的分类体系,例如把世界划分为食物、危险等感知类别。到了认知层面的概念体系,动物是缺失的,非生物更无从谈起。
 
什么是现实?现实到底是什么组成的?看到的,听到的,感知到的,是现实吗?最多就是现实的影子吧。最典型的案例就是世界的五彩缤纷,没有人眼这个感知器,及其人脑的神经处理,我们的色彩体验就不复存在。感知智能尚且如此“虚幻”,更遑论认知智能。
 
“马”的认知大概率是虚幻的,可哲学家门口“那匹白马”却大概率是一个真实的存在。这个矛盾过去无解,现在也还是无解。
 
但是,大模型是建立了概念体系的,当然是一种仿真。最近流行的大模型的压缩理论,我的理解就是蕴含了仿真的人类认知概念体系。说 LLM 通过多层神经一路压缩,压缩造就了机器智能,机器智能因此逼近了人类认知。这看上去非常符合我们从模型中观察到的对世界的惊人的归纳和理解能力。可以说这是大模型最神奇的地方,因为它不仅仅是海量记忆,而是记忆之上也从很多维度对于实体做了归纳抽象,在它的多维向量的大肚子里面,隐形的结构层次是蕴含在内的。大模型的多层压缩很像是人类文明漫长的认知演化过程的一个浓缩版。
 
结构层次的符号化表示就是带有节点的图或树,分为表示概念的非终结节点和表示实体的终结节点。这样来看,哲学家的白马并不是本体的下一级非终结节点,而直接就是那一片叶子,即终结节点。
 
一个假说是,世界本来都是终结的节点,只是人脑容量有限,不得不人为聚类,逐渐建立非终结节点,然后发明了语言来给这些聚类结果强加了分类符号,即概念。人类只有这样烟花,才能把握世界,适者生存,最后爬到了食物链的顶端。
 
有人担心大模型的加速度发展,通过所谓脑机接口,最终会发展出一种永生的超级实体。这种实体超越了碳基生命的脆弱和宿命,带着起源于人类的认知和思想,永续发展为更高级的文明。
 
经过几万年演化产生的人类认知,最多不过是世界的一个幻象。那么,经过几周训练出来的LLM认知,只能是幻象的幻象。影子的影子有一天会统治世界,永续发展,听上去不是匪夷所思吗?但老马与辛顿警告的正是这个威胁。与其远虑,不如近忧,还是先议议人类如何面对正在到来的真假莫辨的世界吧。技术条件已经具备,假象尚未全面泛滥(yet),这只能看成是人类的运气。但时间并不多了。
 
至于机器智能的永续发展,你信还是不信?我不相信!
 
比起文明永生,我觉得白马非马的世界观更加合理。离开人脑,世界就坍缩,本体灰飞烟灭,唯实体长存。死寂、连续、无区别,可能这才是世界的本来面目。凡主观皆幻象。人类智能本来就是幻象,人脑的产物。幻像终归破灭。这很残忍,但却是文明的宿命。哪里有幻象的模型或影子,可以永续长存的呢。
 
 
朋友,您是怎么看大模型的未来,以及人类文明的终局呢?思绪飞扬,欢迎评论区分享您的高见。
 
我是出门问问李维,每次几分钟与您分享AI大模型方面有角度的思考。
 
 
 
【后记】
 

关于白马非马,老友有所批评,很切要害:

信息似乎太浓了。“白马非马”,稍作展开,并提及它的普适性,以有趣故事切入,算是高招;更贴近一点大众,还可以引入“男(女)朋友不是朋友”或“朋友不是男(女)朋友”,巩固一下吸引力;至于实证论(positivism)和建构论(constructivism),应该能够借鉴一些别人的阐释,取简单易懂的语言表达;同理,“模型”部分也会有很好的例子可以借鉴,除了研究的需要,它也是人脑或电脑的自我保护。不纲举目张,人工智能或者人脑都会宕机!模型方法几乎与人同在几千年,“大”模型的大字怎么讲好,有些难度,毕竟新事物可借鉴的先例不多。总的方法是,能够借鉴或者找到答案的东西,则绝不去苦思冥想;好钢用在刀刃上,别人没干过的东西,就手脑并用,尽力造成“子弹很多,目标很小”的局面,用牛刀宰鸡,一举攻克!
“Parsimonious”是一种建模者追求的特性。其实,鲁迅坚持在写作中除去可有可无的字句也是一种parsimonious!
我不喜欢字典里的“吝啬”译法,没有体现“惜墨如金”的意思!
录视频也类似于讲课,力求举重若轻,给人以云淡风轻的感觉[Smile]
老友是老教授,德高望重的老学者,治学、讲学和生活都很严谨,我辈码农,望尘莫及。都是平时闲聊以后汇集的急就章,谈不上思想深邃 也没有精雕细刻。感谢小伙伴的后期渲染,短视频看上去不那么枯燥 平淡了。思绪飞扬 天马行空 也总算雁过留声 马过带风 不至于无影无踪。
 
 
 

AI创作花絮: 《影月无痕》

同一个咒语提示词给img+txt2img,生成了两个形象,反差极大。输入的小雅图片是:

输入的咒语是: 侧面照,girl next door
输出的两幅“侧面照”是:

模型的不稳定表现在,同样的咒语生成了上述玉照,也生成了上面的 monster(?)lol 好在一切都是 copilot,最终由人来拣选和把关,作为图片生成助手,用起来没有问题。

但仔细看,两个形象又有相似之处。寻思可以让大模型写个电影脚本,制造一种剧情,把这两个形象联系起来,例如,白天是美女,晚上成武侠。也许可以演绎一个动人的 drama 来。不妨找当下最先进 ChatGPT4(code interpreter)beta 版来一试?

受到鼓励后,版本2比版本1强太多了,剧情充满了跌宕起伏。

以上的模型表现,退回去一年,是打死也不敢想的。说LLM背后没有上帝,或上帝没有显灵,鬼才信。

 

 

立委NLP《关于系列》

【置顶:立委NLP博文一览】

《朝华午拾》电子版

 

数字人形象设计:为什么选她?

关于数字人的形象,那真是萝卜青菜各有所爱了,最终也是要让用户配置才是出路:配置的结果肯定会出现一批数字人明星,为多数人喜欢。这要到用户群起来以后,会自然呈现。

数字人的形象设计是一个审美过程的落地。我最近推出的女性数字人候选形象有下面几款,都是AIGC生成的,不确定讨喜不讨喜,但都有各自的考量。

为什么选她?

这是一张典型的中国电影杂志封面愿意登载的女星新秀的形象。可以说大俗。但感觉具有代表性。

为什么选她?

因为她让人想起老电影中的女特务。她的眼睛很特别 ,“勾人”。

By the way 对于经历过 wen/ge 的人, “女特务” 绝对是最大的褒义词,虽然当年精神分裂:认知上认为是狐狸精,感性上却忍不住欣赏女特务,不放过女特务的任何镜头。

她肯定不是人人讨喜的大美人形象,但别有特点。现如今生成漂亮或艳丽的形象很容易,但要生成有特点有好看的人,就不容易了。因为人都越来越挑剔。

 

为什么选她?

就是一个黄毛丫头,但并不俗气。她让我想起其身世可能是流落在民间的皇家公主。如果精心挑选合适的配音,她作为数字助理 应该会满足一些人的偏好的。

为什么选她?

你不觉得她太萌了吗?完美符合国人对金发小女孩的定义。当然,配音还可以再做适配,这些数字IDs 都具有一定的可以持久站住的理由。

为什么选她?

老友建议把她改名为小稚,像个女孩子的名字,我觉得有理。

小稚是小雅以后最接近小雅的艺术肖像了。自从半年前我千里挑一 ,创造并营销了小雅的独特数字ID以来,就再也无法创作类似的数字人形象了,让人感叹艺术创作的可遇不可求。难道小雅就成为我数字人形象创作的绝唱,连一个替代者都没有可能?

小稚就是作为替代者推出的,气息上接近小雅,所以戏说她是小雅的 twin sister。当然,她不如小雅,形象独特性不够。

回看一下小雅的数字形象:她的解说,她的歌唱,是不是一个已经可以活起来了的数字ID?进一步的工作就是借助大模型给她塑造有趣而独特的性格和灵魂了。

小雅绝对不是完美的形象,她甚至眼睛有瑕疵,对不上焦,但作为艺术肖像 她有站得住的独有的清新气质。

小雅的原作如下,被批评为穿着太西方,我让 txt2img 给她换一套服装,结果模型决定给她盖了一条毯子 lol

诗云:

蒹葭苍苍,白露为霜。所谓伊人,在水一方。溯洄从之,道阻且长。溯游从之,宛在水中央。

AI浪潮博客目录

大模型的落地现状和前景

大家好,我是李维的数字人分身。 今天谈一下大模型的问题。L LM 的命门已经蛮清晰了:幻觉+随机性。 幻觉与随机性有关联,但角度和外延不同。 幻觉的主要表现就是细节遗忘+细节编造,所谓“一正胡八”。 其所以遗忘,是因为该信息的冗余度不够,大模型只能把它当成数据噪音。 其所以编造,是因为语言模型的丝滑本性决定的: 不能留白,需要找到最符合语言习惯的细节替代品。 于是张冠李戴、指鹿为马了。 随机性比幻觉表现更加广泛,表现为结果的不稳定性,那是所有概率模型包括LLM的本性。 牵涉到的不仅仅是细节的随机编造,也包括解决路径的方方面面的不稳定(例如 LLM agent 的思维链,计划,行动,反思和反应等等)。 LLM 里面的确积攒了很多历史解决方案,LLM 在合适的 prompt 催逼下也的确可以把这些方案勾引出来。 但是这些解决方案具有随机性,无法应对长线条的业务逻辑。 据说,目前的水平是5步限制,任何线条超过5步,绕5个弯,LLM 的 agents 就晕菜了。 这些表现注定了LLM在两类应用场合不同的命运: 第一类是生成创意类的场合,还有聊天的场合,那完全是洗牌、碾压。 那种场合追求的不是正确性,而是多样性、创造性、丝滑性和 human-like。 在这里,幻觉+随机性与创造性是同义词,起的是好作用。 第二类是垂直领域知识场景,以及有些需要精细逻辑或计算的场景。 这里基本上不能容忍幻觉+随机性。 这第二个场景,本质上需要跳出三界外。 就是说,很可能需要跳出大模型,去寻找尽可能具有某种通用性的 beyond LLM 的解决方案和框架。 把 LLM 只当成一个重要的资源来利用,当成 api 来调用,而不是指望LLM主导来搞定领域。 此外,LLM 还有一个问题。 在我们欢呼 LLM 听懂人话的同时,我们现在所追捧的 prompts 变得特别重要。 所谓 prompts 就是人话指令,但是人话本身也有沟通的“艺术”。 这种艺术化的交互手段,作为与机器打交道的 vehicle,具有自然语言本性上的短板,就是模糊性、线条性,缺乏层次、结构和逻辑。 这其实是交互的进化,效果的退化。 交互上,只要会讲人话,大家都突然成为“码农”了,可以直接对机器吆三喝四,感觉很爽,很亲民,很接地气。 机器终于低下高贵的头颅,开始迁就人类的模糊。 但是效果上肯定是退化的,因为指令不再是明确的、逻辑的和精细的。 这是自然语言代替电脑语言难以回避的表达缺陷,一定会影响LLM的实效。 这些都是大模型从本性上带来的问题,也是目前做大模型领域落地人员的共同挑战。 大家都在苦苦挣扎,试图找到解套的良策,希望在大模型与领域对齐的过程中,能够外挂领域数据和知识库,探索场景业务逻辑的带入。希望能有突破。 我是出门问问李维,每次两分钟,与您分享大模型有角度的思考。
 

大模型漫谈系列n

昨天创业邦发文《第一批AIGC独角兽已经在吃散伙饭了》,讲的是 Jasper 由盛而衰的故事。
这故事写得细节生动,好惨烈,强调的是护城河。
Jasper 兴起在 GPT3 的时代,当时 GPT3 是个“裸机: 没有“咒语”敲不开门。
于是会念咒语的 Jasper 就成为呼风唤雨的巫师。
当时谁会想到 few shots 咒语这么快(也就两年光景)突然退位,被所谓zero shot 的ChatGPT所取代 : 机器学会了人话。
于是, 大水冲走了龙王庙。巫师成了哑巴。
这其实不能怪巫师没建自己的护城河,咒语本来就是一条河。
怪就怪命运无常, 一条河挡不住一场洪水。
这故事太具戏剧性了。
最大的恐怖不是巫师的失业,而是洪水摧毁了很多 AI-GC 产业。
当人人可以吃得起山珍海味自助餐的时候,餐饮业还有繁荣的可能吗?
历史上,机器翻译产业就是这么被做死的。
现在这场洪水摧毁的岂止是翻译, 它摧毁的是整个 nlp。

前一阵子受邀做巡回演讲, 让我谈架构师的焦虑 。
焦虑也是一个热词了, 现代人几乎没有不焦虑的。
越是高级劳动, 越是打工贵族, 就越焦虑。
架构师的焦虑可谓一个典型。
我告诉架构师们: 你们焦虑了, but you are not alone!

你知道 最焦虑的是谁吗?
你很难想象,在nlp大革命的漩涡中心,nlp从业者实际上最焦虑。
几乎被团灭。一夜醒来,干了一辈子的职业,突然消失了。
你能想象那是一种什么感觉。
现在还有人自称nlp专家吗?
什么机器翻译专家、 自动摘要专家、 信息抽取专家、 情感分析专家、 汉语分词专家、 计算风格专家、 辅助写作专家、 电脑对联专家、 问答系统专家、 聊天机器人专家、句法解析专家、篇章分析专家 …… u name it。
所有的专家加在一起,不如一头驴。
刀郎曰过:那马户又大又蠢, 还有16个头。
横冲直撞,摧毁了一个个nlp产业。
以前我说过是, 有了这头听得懂人话的驴, 那就为大众创业创造了条件。
这话其实也不错,如果你真能找到那个角度和服务对象。
但目前看到的景象却是一片惨淡:这头驴扼杀了很多可能的生机。
终局呢?
还是我以前说的二分法: 洗牌和洗礼。
这头驴在洗牌的时候,以碾压之势,摧毁了一切“浅直”的nlp产业。
但还有很多接受洗礼的垂域或场景, 它似乎还够不着。
现在就处于这种胶着状态:每个人都觉得llm无所不能,但眼看着它落不了地。
开始了新的一场焦虑和对AI的失望情绪。
要知道,现代人,包括投资人,耐性都极为有限。

看热闹的话,百模大战目前可能还是最大的盛世景观。
几乎所有的llm,都在疯狂烧钱, 而能拿它赚钱的寥若晨星。
不用太久, 有几家大模型经得起这么烧钱、烧电力呢。
烧完之前, 能落地的就是幸运儿了。

且看
且叹
且珍惜。

我是出门问问李维,每次几分钟,与您分享大模型有角度的思考。

图片一键生成短视屏,奇妙元是时间的摄像机

这不是我,是我老爸的学生时代留影。

小雅谈图片一键生成短视屏。

IGC 让老照片开口说话!让你care的人惊喜 让父母家人会心一笑。让肖像动画 让雁过留声。让时间定格 让回忆鲜活。让两情相悦永不褪色 让你的青涩不染俗世的灰尘。让爱人永远美丽 让老同学永远年轻。让擦肩而过回眸一笑 让生活不至于随风飘去。让形象超越一场梦 让存在不再是无影无踪。奇妙元小程序的图片一键生成 是生命的摄像机 带你穿越时间隧道 给你无限遐想感念。同款制作 零门槛 限时免费 你还等什么?让活着不仅仅是活着 而是情的传播 心的连接。

我用AIGC制作的小雅艺术肖像 原作一直有人觉得穿着太西方 我就让 txt2img 换一套服饰 没想到模型给小雅盖上了毛毯 lol。

小雅教给你一步步做图片一键生成。

奇妙元数字人实验场(4):family

奇妙元数字人实验场(2)

奇妙元数字人实验场

这是我最近尝试自家的奇妙元的图片一键生成短视频,或者我的2.5D克隆数字人的一些短视频。效果如何?

 

喜欢刀郎,也喜欢那英

想说的是,喜欢刀郎,也喜欢那英。可以理解刀郎对那英的讽刺,也可以感觉那英的郁闷,但相信那英的性格。

文字驱动奇妙元 几秒钟制作短视频:我表妹说得似乎有理:罗刹海市的歌词,要是鸡蛋里挑骨头,还是能挑一点点的,比如,可是那从来煤蛋儿生来这黑,不管你咋样洗呀那也是个脏东西,这一句有点毛病,煤蛋儿黑,黑就是黑,你不能说脏,黑与脏是两个意思,你说对不对?
对啊,黑等于脏就是种族歧视[Grin]。黑 与 洗白 对得上 完全没有脏出场的必要。可刀郎不骂几句 如何解气。居高临下 雅俗交融 十载一吼 过足了骂瘾的他 但愿可以活得平和些 看后去还能出啥好作品。有意思的是,骂人骂到了化境不算,自夸也到了无以复加。小伙儿马ji,出淤泥而不染,所有的美好集于一身。刀郎是读过文学的,估计会背《离骚》,手法学屈原。美人香草,偏遇昏君小人,郁郁不得志。马户-驴,又鸟-鸡,刀点-刃,良部-郎。女子不好,心刀点忍?点解?无解。发泄也是一种解。

奇妙元体验AIGC奇妙:《岁月如歌:神秘园》

神秘园欣赏笔记 -- 奇妙元 2.5D数字克隆解说

在下数字分身(奇妙元 2.5D形象克隆+声音克隆)

这一位是我自己半年多前txt2img创造的艺术肖像。现在配上网上最流行的女声,也是我最喜欢的女配音,叫小柔。

( ---- 做奇妙元小白鼠,体验奇妙。尝试最新 features,给小伙伴 report bugs。)

奇妙元:https://weta365.com/main/

《AI浪潮:ChatGPT 的传统与开放的NLP 能力》

 

信息抽取

这条新闻讲的是美国共和党遭遇议长选举的闹剧和挑战。送进去,我让它给我抽取:(1) 实体;(2)引语;(3)关系;(4)事件;(5)情感分析。用的是大白话,这些以前都是 NLP 的专项任务,现在“zero shot”它,给个指令即可。

情感分析显示了其NLP的超能力。传统的 sentiment analysis 不过是一个正负二级分类。在这里不大合适,而它会把带有情绪的洞察(insights)抓出来,显得非常灵活精当。

自动摘要

以上算是传统的NLP任务零样本测试。下面也看看其他文字类任务的表现,表现其NLP新能力。意想不到的能力发掘的根本原因是听懂了人话。在此之前,NLP 社区为了定义一个任务,需要耗费很多的精力去设计目标,准备数据和统一标注标准,组织社区竞赛。这就必然限定了任务的种类。现在每个人都可以尝试让它做各种任务,人民群众的创造力得到了极大的发挥。以前太多的死角,现在都可以去尝试。

推荐信

自从 chatGPT 横空出世,应用文辅助写作案例已经水漫金山,见奇不怪了。但这不改变辅助写作是一个具有巨大应用场景和价值的方向,虽然大概率与机器翻译也差不多,最后作为行业可能被做死,或成为白菜价。下面是我自己前一阵子做的一些试验,摘录如下。

请帮助我用规范的英文写一篇推荐信,内容包括:1. 推荐张三到清华做博士后,研究AGI;2. 我是张三的博士导师; 3. 张三博士论文获到全国优秀论文大奖。

Dear Admissions Committee,

I am writing to highly recommend Zhang San for admission to your PhD program in AGI research at Tsinghua University.

As Zhang San's doctoral advisor, I have had the pleasure of working with him for the past three years and have been consistently impressed by his intellectual curiosity and dedication to his research. His thesis on AGI has been recognized with the National Outstanding Thesis Award, a testament to the quality and originality of his work.
In addition to his impressive research abilities, Zhang San is a team player and has proven to be a valuable asset to our research group. He is able to work well with others and consistently contributes fresh ideas to our discussions. I am confident that he will thrive in a collaborative environment like your PhD program.

I strongly believe that Zhang San would be an excellent fit for your program and would make a valuable addition to your community of researchers. I wholeheartedly endorse his application and hope that you will consider him for admission.

Sincerely,

[Your Name]

请增加一些具体生动的细节,让推荐信更为有力。

Dear Admissions Committee,

I am writing to highly recommend Zhang San for admission to your PhD program in AGI research at Tsinghua University.

As Zhang San's doctoral advisor, I have had the pleasure of working with him for the past three years and have been consistently impressed by his intellectual curiosity and dedication to his research. His thesis on AGI has been recognized with the National Outstanding Thesis Award, a testament to the quality and originality of his work. In particular, his contribution to the development of a novel AGI algorithm has garnered attention from researchers in the field and has the potential to significantly advance the state of the art.

In addition to his impressive research abilities, Zhang San is a team player and has proven to be a valuable asset to our research group. He is able to work well with others and consistently contributes fresh ideas to our discussions. I have seen him take the lead on several collaborative projects, always ensuring that all team members are on the same page and making valuable contributions to the final product. I am confident that he will thrive in a collaborative environment like your PhD program.
I strongly believe that Zhang San would be an excellent fit for your program and would make a valuable addition to your community of researchers. I wholeheartedly endorse his application and hope that you will consider him for admission.

Sincerely,

[Your Name]

好了一些,但请增加下列事迹:1. 废寝忘食 他总是最后一个离开实验室;2. 发表了5篇一级刊物论文,成为青年学术新星;3. 虽然AGI被认为是难以实现目标,张三在定义AGI实现的不同步骤上提出了具有操作性的建议,并实现了10个步骤中的前5个。

Dear Admissions Committee,

I am writing to highly recommend Zhang San for admission to your PhD program in AGI research at Tsinghua University.

As Zhang San's doctoral advisor, I have had the pleasure of working with him for the past three years and have been consistently impressed by his intellectual curiosity and dedication to his research. His thesis on AGI has been recognized with the National Outstanding Thesis Award, a testament to the quality and originality of his work. In particular, his contribution to the development of a novel AGI algorithm has garnered attention from researchers in the field and has the potential to significantly advance the state of the art. Zhang San has also published five papers in top-tier journals, establishing himself as a rising star in the field of AGI research.

Despite the challenges and setbacks that are inherent in AGI research, Zhang San has remained committed to his work and has often stayed in the lab long after everyone else has gone home. His dedication to his research has paid off, as he has already achieved significant progress in his work. In particular, he has proposed operational steps towards the realization of AGI, and has successfully implemented the first five steps of his proposed framework.

In addition to his impressive research abilities, Zhang San is a team player and has proven to be a valuable asset to our research group. He is able to work well with others and consistently contributes fresh ideas to ......

中国教授头疼的为学生写推荐信问题,已经完美解决。只要你能列出零星哪怕是散乱的要点,机器就会给你拽成一篇看上去非常 professional 的规范推荐信。有没有问题? 当然可能有。例如明明是要求博士后推荐,它写成了 to your PhD program, 但关键是语言方面的困难都给你搞定了,只要通读一遍把个别词改正一下即可。

写段子

还行吧,这些段子水平不高。但比憋不出来强。

本来写出好段子就是最具挑战性的人类创作活动之一,只要采访几个著名的脱口秀演员就知道其中的甘苦了。很多大火的脱口秀演员,为此绞尽脑汁。台上五分钟,台下无数不眠夜。让人开口笑,并不容易啊。

wow,不知道这是抄袭的,还是“涌现”的,联想一下还真像是个搞笑的段子:

gou (go) 我不会飞,可我很快。
niu 所以我那么大(大妞儿?)

猫猫 miao 或 mao, 耗子 mou,也蛮形象,有声有色的样子。

哈,看来只学会了一个套路:羊/yang (young),所以我害羞。

写情书

ChatGPT 写情书不重样。这是陷入爱河但苦于笨嘴拙舌的人的福音了。

人的爱意,哪怕有套话,也是要表达才行,藏在心里不行。“I love you” 是鹦鹉学舌完全可以做到的,但并不因为是套话而失去其神奇效应。无数的情感矛盾和关系恶化,其实就是缺少了这三个字的表达频度。

但热恋要求更高一点,需要营造浪漫。营造需要形式,而有的人就是不懂形式,不善言辞,不会表达(俗话说,不会来事儿 lol)。你便是真情如海,但羞于表达或表达不出来也没戏。谁愿意与木头谈一场恋爱?

有问,机器代写的情书能有真情吗?这就好比询问:毛笔写的情书能有真情吗?ChatGPT 不过就是个工具,就跟你用毛笔还是钢笔一样。这个工具见识过无数的情书。工具帮助你产生形式,至于真情表白还是虚情假意,那要看使用工具的人了。

顺着这个话题延伸一下,说说 chatGPT 作为文字助手的作用,尤其是对于不善言辞的人。

出口成章的人是少数。见过很多人在一些场合需要应景,却憋不出话来,十分窘迫。现在好了。不知道有没有办法把 ChatGPT 制成一个可以植入的东西,就不说老马说的脑机接口了,只要能让它成为一个隐藏的招之即来,但无人察觉的暗器,也许类似传说中的苹果眼镜,让它编制的应景台词,跟提词器似的,崩到眼镜上,我见人不见。那会是社恐人士多大的福音。

不同程度的社恐据报道是一个相当普遍的困扰,我自己也深受其害:人稍多就哑巴了,插不上话,却要硬着头皮应付。看社交场合如鱼得水的人,知道他们是胡喷,但人家给气氛啊,自己啥贡献也没有,成为社交累赘。有情商的的人,还要照顾你情绪,不时还要引一两句给你,带你玩的意思。ChatGPT 可以改变这一切,让笨嘴拙舌秒变伶牙俐齿,让只懂本行的老专家也能成为百科地保。 

看到一条朋友圈信息: “ChatGPT是中庸主义者的福音,完美地让你泯然众人、符合社会的基本期待。ChatGPT不需要提升生产力(不需要empower人类的语言能力),只需中庸地鹦鹉学舌,帮助人类在其没有表达意愿的场景、完成表达的义务。”

 

 

《AI浪潮: 辛顿的 AI 威胁论与马斯克如出一辙》

前些时候的一条爆炸新闻来自纽约时报:

伊弗里·辛顿 (eoffrey Hinton) 与另外两位所谓的“人工智能教父”一起获得了 2018 年图灵奖,以表彰他们的基础性工作导致了当前人工智能的繁荣,现在他表示自己的一部分对自己一生的工作感到遗憾。根据《纽约时报》对这位 75 岁老人的采访,欣顿最近辞去了在谷歌的工作,以便畅所欲言地谈论人工智能的风险。

“我用通常的借口安慰自己:如果我没有这样做,其他人也会这样做,”已在谷歌工作了十多年的 Hinton 说。“很难看出如何防止坏人利用它做坏事。”

听上去,与原子弹制造者或投放者的反省、懊恼类似。辛顿团队在10年前的深度学习元年在 ImageNet 图像识别大赛中以CNN碾压以前的所有机器学习系统,随后被谷歌请去。他在谷歌的10年,是AI的爆炸性发展的10年。

“正是这项工作最终促成了 ChatGPT 和 Google Bard 的诞生。
这位终身学者在谷歌收购了一家由 Hinton 和他的两名学生创办的公司后加入了谷歌,其中一名学生后来成为 OpenAI 的首席科学家。Hinton 和他的学生开发了一个神经网络,在分析了数千张照片后,它可以自学识别狗、猫和花等常见物体。正是这项工作最终促成了 ChatGPT 和 Google Bard 的诞生。

根据NYT 的采访,Hinton 对谷歌对该技术的管理感到满意,直到微软推出新的 OpenAI 注入的 Bing,挑战谷歌的核心业务并在搜索巨头内部引发“红色代码”反应。Hinton 说,如此激烈的竞争可能无法停止,导致世界上充斥着如此多的虚假图像和文字,以至于没有人能够分辨“什么是真实的”。

但这只是 Hinton 最关心的问题。在更长的时间内,他担心人工智能会消除死记硬背的工作,并可能随着人工智能开始编写和运行自己的代码而消除人类本身。

“这种东西实际上可以变得比人类更聪明的想法——一些人相信了,”欣顿对纽约时报说。“但大多数人认为这还很遥远。我认为这还很遥远。我认为它是 30 到 50 年甚至更长的时间。显然,我不再这么想了。”

就是说,以前以为还有半个世纪的人类反应和防范的时间,可是显然所有人都没有想到科技发展的加速度涌现。所以:

1. 我们已经进入真假莫辨的时代,但人类没有准备好如何应对;

2. 人类飞蛾扑火似地加速AI进程,生产力的提升和资本的回报所带来的兴奋和诱惑不可抵挡。

怪就怪当年辛顿用CNN炸平ImageNet后,突然有了商业算计,搞什么竞标拍卖,于是率团投入谷歌。要是随了百度(第一个追求者),何至于今日。没有谷歌,就不会有 Open AI;没有Open AI,就不会有 chat;没有chat,人类社会就依然是 good old days。

鲁老师说,嗯,这个思维链是没问题的。lol

马少平老师说,辛顿凡尔赛。

没见过这么巨大的凡尔赛了,绝对创迪尼斯纪录,而且后无来者。人家也有这个底气和资格,千年不遇。他这一来,对于AI威胁的社会警醒,秒杀老马的呼吁,以及那封成千上万名人的公开信。名人效应的极化表现。

世界上唯一可以更加“凡尔赛”的事件想来只能是爱因斯坦了,如果老爱生前高调表示自己后悔发现了质能方程 E=mc²,因为它促成了原子弹。

我当时说,估计还会有后戏。果然,最近,辛顿有一个长篇访谈: 人类可能只是AI演化过程中的一个过渡阶段。这与马斯克的说的“人类可能只是硅基生命体的引导程序”如出一辙。这两位毫无疑问是AI威胁论的最有影响力的呼吁者。

辛顿:如果你看看这些大型语言模型,它们有大约一万亿个连接,像GPT-4这样的东西知道的比我们多得多,它们具有关于所有事物的常识性知识,它们可能比一个人知道的多1000倍。

但是它们只有一万亿个连接,而我们有100万亿个连接,所以它们比我们更擅长将大量知识放入仅一万亿个连接中。

我认为这是因为反向传播可能是比我们拥有的更好的学习算法。

这是可怕的。

纯粹从数字看,辛顿说,

1. 已知 GPT4 比我们人类的知识量多了三个量级(千倍)

感觉上这是保守的估计,assuming 作为个体的人,甭管什么专家。

2. 人类大脑的神经元比 GPT4 数量高了两个量级

这种类比合理与否存疑。是不是 apples to apples,另外,人类很多神经元并不直接参与智能工作。等等。

3. 结论:(算法)原理上,back prop (反向传播) 比人类的内部学习机制(天知道是什么)更加高效。

主要是说,电脑比人脑聪明。

辛顿花了很长时间解释反向传播(back prop)算法,试图用中学生能听懂的语言解释,感觉是很好的大师科普(让人想起小时候爱看的华罗庚给中学生普及的数学原理):

主持人:

在谈论GPT-4的前景之前,让我们回顾一下反向传播,以便我们都理解你提出的论点,并告诉我们反向传播是什么。这是一个算法,你在1980年代与几位同事一起开发的

Hinton:

许多不同的小组都发现了反向传播,我们做的特别之处在于使用它,并表明它可以发展出良好的内部表示。有趣的是,我们是通过实现一个很小的语言模型来做到这一点的。它的嵌入向量只有6个组件,训练集有112个案例。大约10年后,Yoshua 使用基本相同的网络处理自然语言。如果使网络变得更大,它实际上应该适用于自然语言。

反向传播的工作原理,我可以为您提供一个简单的解释,知道它如何工作的人可以得意的坐下来,嘲笑我提出的解释方式,好吗?因为我有点担心它不够好。(观众笑)

想象一下,你想要在图像中检测鸟类,所以在图像上,假设它是100像素×100像素的图像,那是10,000个像素,每个像素有3个通道,红绿蓝,那是30,000个数字。计算机视觉问题是如何将这30,000个数字转换为是否存在鸟类的决策,人们试图长时间做到这一点,但他们做得不是很好。

这里有一个建议,你可能会有一层特征检测器,检测图像中的非常简单特征,比如边缘。所以一个特征检测器可能有很大的正权重对应一列像素,然后对邻近的一列像素有很大的负权重,所以如果两列都很亮,它就不会启动;如果两列都很暗,它也不会启动,但如果一侧的列很亮,而另一侧的列很暗,它会非常兴奋,那就是边缘检测器。

我刚刚告诉你如何手动连接一个边缘检测器。我们可以想象一个(神经网络)有大量的类似检测器检测不同方向和不同尺度的边缘来覆盖整个图像,我们需要(检测)相当多的数量。

主持人:

你是指线条,例如一个形状的边缘。

Hinton:

从亮到暗的地方变化的地方。嗯,就是那样。

然后我们可能在上面有一层检测边缘组合的特征检测器,例如,我们可能有一个检测两个边缘以尖锐角连接的特征检测器。如果这两个边缘同时出现,它会变得兴奋,那将检测到可能是鸟嘴的东西,也可能不是;在那一层,还可能有一个特征检测器检测到一圈边缘,那可能是鸟的眼睛,可能是各种其他东西,可能是冰箱上的旋钮之类的东西;然后在第三层,你可能有一个未来检测器,检测潜在的鸟嘴和潜在的眼睛并连接起来。继续这样连接,最终可能会有一个检测到鸟类的东西。

然而,手动连接所有这些内容将非常困难,决定应该连接什么权重应该是多少,尤其困难,因为你希望这些中间层不仅适用于检测鸟类,还适用于检测各种其他事物。所以这几乎不可能手动实现。

反向传播的作用是从随机权重开始,这些特征检测器完全是垃圾(不真也不能用)。然后你放进一张鸟的图片,输出可能是0.5表示是鸟(假设你只有鸟和非鸟)。接下来,你需要改变网络中的每个权重,让它不再说0.5,而是说0.501表示是鸟,0.499表示不是鸟。你需要改变权重的方向,使得更可能说鸟是鸟,更不可能说非鸟是鸟。这就是反向传播的原理。

反向传播实际上是如何消除差距,在你想要的(也就是概率1表示是鸟)和现在得到的(也许是0.5)表示是鸟之间。如何消除这个差距,把它反向传播到网络,这样你就可以计算网络中每个特征检测器,你希望它更活跃还是更不活跃。一旦你计算出来,如果你知道你想要一个特征检测器更活跃一些,你可以增加权重,来自特征检测器的权重,并也许加入一些负权重到特征检测器。这样,你就有了一个更好的检测器。

所以反向传播就是反向遍历网络,找出每个特征检测器,你是否希望它更活跃一点,还是更不活跃一点。

back prop 实在太关键了,是深度革命的命根子,是LLM智能的学习机理,值得反复科普。

辛顿的下一个论证,说的是为什么AI可怕。

简单说,就是模型可以复制,而人脑不可以复制:一个师傅要培养出一个同等知识的徒弟需要经过漫长的教育过程。辛顿论证说,LLM 可以复制任意份,每个 LLM 可以去根据不同领域的更多的数据做微调(他没说是 fine tune,但从复制的基础模型的源头以及会改变模型权重看,他指的是 fine tune,而不是随学随忘的 in context learning)。

这些被微调了的不同专家模型可以有效沟通,只要不发生直接冲突,他们所学到的新的专业知识(新的模型权重)可以互通有无,最后形成更超级的大脑模型。辛顿论证的这最后一步,也许我孤陋寡闻,没见这种有效沟通成为更强模型的学术报道。但他这么说,觉得应该相信他。

可复制,可融合。有了这两条的 AI 演进,于是人类面临一个完全超出我们想象和理解的可以野蛮发展的新的智能形态。

它们可以学到更多的东西。以一个医生为例,想象一下,有一个医生,他已经看了1000名患者,另一个医生已经看了1亿名患者,你会期望,第二个医生如果没有太健忘,他可能已经注意到了数据中的各种趋势,而这些趋势在只看过1000名患者的情况下是看不到的。

第一个医生可能只看过一个罕见病患者,另一个看过1亿患者的医生已经看过很多这样的患者,所以他会看到一些规律,这些规律在小数据中是看不到的。

这就是为什么,能够处理大量数据的东西可能看到的数据结构,我们永远看不到。

这就是我们以前议论过的情形:在超大数据超大模型中,原来的小数据不再稀疏,因此可以“涌现”出新能力、新知识。

接下来,辛顿举的下面这个例子我觉得并不牢靠、鲁棒(完全可以从非严格常识推理的其他角度解释他列举的案例)。不过,他所感受到的 GPT有时候让人惊掉下巴的推理能力,我们都曾在不同的案例中感受过多次,虽然并不是每一次都经得起严格检验,但这种感觉是真实的、普遍的。

主持人:

那么,给一个我应该对此感到恐惧的点?

Hinton:

好吧。请看看GPT-4,它已经能够进行简单的推理。我明白推理是我们人类的强项,然而,GPT-4在几天前展示出的表现使我感到震惊。它完成了我认为不可能的常识性推理。

我问它,我想要我房子里的所有房间都是白色的,目前有一些白色房间,一些蓝色房间和一些黄色房间,黄色油漆在一年内会褪成白色。那么,如果我想要两年后所有的房间都变成白色,我应该怎么做呢?

它回答说,你应该把蓝色的房间漆成黄色。尽管这不是直观的解决方案,但它是正确的。这相当令人印象深刻。

这种常识性推理,用符号AI很难实现,因为它必须理解什么是褪色,它必须理解时间问题。所以,它们在做一种合理的推理,智商大概是80或90左右。

正如我的一个朋友说的,这就好像基因工程师声称,我们要改进灰熊,我们已经把它们的智商提高到65了,现在它们能说英语了,而且在各种方面都非常有用,但我们认为我们可以把智商提高到210。


主持人:

我有过,相信很多人也有过类似的感觉:与这些最新的聊天机器人互动时,脖子后面的头发会竖起,有一种奇怪的感觉。

但当我感到不舒服时,我只需关闭我的笔记本电脑。。。

辛顿说:“政治系统如此破碎,以至于我们甚至不能决定不给那些十几岁的男孩攻击性武器。如果你不能解决那个问题,你如何解决这个问题?”

说的是美国的枪支泛滥,到了几乎每两天就有一次滥杀无辜的恶性案件出现,而政治家无所作为。这种德行的人类社会,我们还敢指望它能应对AI威胁吗?在这样的人类世界,辛顿的警钟是:

“我不认为我们会停止发展它们,因为它们非常有用。它们在医学和其他方面都非常有用。所以,我不认为有什么机会阻止发展。我们想要的是某种方法,确保即使它们比我们聪明,它们会做对我们有益的事情。这就是所谓的对齐问题。

但我们需要在一个有恶意行为者的世界里尝试这样做。他们想要制造杀人的机器人士兵。对我来说,这似乎非常困难。”

技术是中性的,很多人拿技术做好事,但怎么防止坏蛋拿技术做坏事呢,例如制造机器人士兵。

辛顿的最后结论,与马斯克完全一致。这很有趣,不是简单的英雄所见略同。辛顿是这场AI技术革命的源头,是最有资格从技术角度看人类命运问题的人选。马斯克本来是局外人,他对于技术的了解跟我们一般人本质上无区别。当我们上升到人类命运的角度,当技术必须从哲学或更广的视角去审视的时候,山内人与山外人所见完全相同,这是辛顿受了马斯克影响呢,还是辛顿受了马斯克影响呢?lol

从时间线条的唯一性上看,只能是深度学习之父受到了一个技术商人的影响,而不是相反。我不大相信,这是辛顿独立发展出来的AI威胁论。更可能的是,老马发表“高论”后,辛顿开始是持怀疑态度的。随着LLMs的推进,尤其是 GPTs 系列的发布,特别是 GPT4 的出现,辛顿开始接受,并信服了老马的观点。然后他开始从技术角度做“权威”阐述。

老马的高论中最著名的比喻以前说过,他把在超级智能面前的人类比做蚂蚁,说:超级智能对于人类不必有恶意,他们对人类没有恶意,但这并不妨碍他们消灭人类。因为根本就不需要恶意,只要人类在超级智能的实现目的的路上挡道了,就好比人类在开一条路的时候遭遇了蚂蚁,我们并不需要对于蚂蚁的恶意,我们会不眨眼睛就把挡道蚂蚁铲平。

人类其实就是蚂蚁。

辛顿在比喻中,异曲同工,他一再把人类比做两岁的儿童,把超级智能比做成年人。一个成人操纵一个两岁儿童,太容易了。比如你给儿童两个选择,儿童的智商是不会想到还有第三种选择的。

在野蛮发展的LLMs面前,人类就是这么可怜。

我以前觉得这种AI威胁论有耸人听闻之嫌,但也找不到对此的有力反驳。起码,在我们难以想象的加速度发展的AI智能面前,人类如何自处,始终是一个很难想象的挑战。

外一篇 斯坦福五月7日记

有朋自远方来,天气好。下了几天雨,今日转晴,不热不冷。

与黄老师一路辩LLM哲学,@梁焰 从旁添油加火,时有妙语内插(interpolation), 警句外推(extrapolation),人智涌现,不亦乐乎,此斯坦福之记也。

我们的共识是:人与机器肯定不同,但机器从表现上无限接近于人。

黄老师坚持,只要机器不是人,就肯定会有软肋人类可抓。窃以为并非如是简单,例如, LLM 无以离散符号程序化,无论步骤几何,非透明逻辑可解。人类乃逻辑生物,既如此无知,何来抓其软肋,人类胜机器之一筹?是故辛顿与老马之忧似非空穴来风。

我故信人之异于机器者几希,莫名某点而已。盖因面片咸为AGI侵蚀殆尽,创造性几近失守,自主性面临夹击,鲜能辨其异何在。黄老师言,人与机器本质不同,机器纵为悟空,亦跳不脱人类如来之手心。(听上去类似马云的论调?) 

思辩乘兴而起,兴未尽而暂停,无解而终,复归俗世。

是日也,天不高而气爽,人不多而闲散。绿草成茵,白塔耸立,三五儿童,嬉戏其间,现代伊甸园之乐也。今日何日,LLM有知乎?GPT4 奈何之?

唯愿此景长存,杞人忧天。

令 ChatGPT4 将以上文白夹杂日记改写为文言,得文如下:

 

 

 

【相关】

AI教父最新MIT万字访谈: 人类可能只是AI演化过程中的一个过渡阶段

《AI潮流:开发者提示工程公开课中的二原则》

Andrew 春风满面,亲自参与的这个提示工程的课程,很浅显易懂,肯定会风行。Andrew 说,稍微复杂一点的任务,没有一个好的 prompt 是一枪命中的,总要反复尝试 最后才满意。这与码农编程序一样,谁不经过反复调试就能写出好的程序呢。

然后他说,LLM 的好处是你可以反复跟它磨叽,不管啥事。要是以前的 AI,你得一个一个的任务去建模,每个任务从标注数据,培训模型,测试,部署,好不容易上线了,结果换了个任务,所有的过程要重来一遍。现在这样一个 LLM 你反复“压榨”它,它的知识和学问如此之大,好像榨取不完,可以做各种任务,的确是范式转变。

【原则1: 提示要具体】

提示工程首先要 “write clear and specific instructions”.  这个其实大家都有体会,跟 chat 这种庞然大物玩,它脑袋那么大,里面的“知识/思想/意义”的电路各种节点,纵横交错,相互勾连,密密麻麻。要想用提示词激发让你满意的回应,就需要确保所激发的那一小块电路对应了你所想得到的答案。你的提示词越具体(表达了你心中的疑问就越确切),chat 的回答自然也越对路。这个道理和体验很容易get,但具体的技巧需要细化,这就是上课的好处。

【原则1技巧1:使用分隔符】

“The first tactic is to use delimiters to clearly indicate distinct parts of the input.”  什么意思?就是要求提示词中首先要把任务指令与任务的处理对象分开,要求用分隔符把处理对象明确标出来。这一点,多数人容易忽略,结果是,chat 经常把任务的某些描述词也当成了任务的对象,或者把任务的处理对象当成指令的一部分,这在逻辑上叫做层次纠缠(任务是“元语言”,对象是待处理的输入语言,不可混淆)。这个毛病我以前也常见,一直没意识到这其实是因为对提示词层次不够注意,违反了第一原则的第一技巧实操(best practice)。

这里 delimiters 就是引号。chat 就知道这是其摘要处理的对象。否则,如果提示词中任务描述较长,模型有可能把任务本身也当成所要处理的对象,以前遭遇过这种后果的。

【原则1技巧2】让模型输出表格化。

“This tactic is to ask for a structured output.” 提示词任务中最后加一句:in tabular/json/html format with the following keys: Key1, Key2, Key3。很多时候,表格化输出看上去更酷,也更方便后续存贮和处理。

【原则1技巧3】可以用 IF ... THEN ...

原讲义说的是:“to ask the model to check whether conditions are satisfied”.  这实际上就把编程中最重要的条件分叉能力带入了自然语言提示词的指令。一般人想不到提示词还可以这么做。可以用自然语言模拟程序代码,让机器分别不同条件决定采取何种动作。

if-then 你学会了吗?

宋柔:你问它:第一步中洗净五花肉的动作者是哪个,第六步中把什么下入温水,第十步中出锅食用的是什么。

难不住它吧,它不仅仅是大号鹦鹉,它有(一些)常识。

宋柔:但是我估计最后一个问题“第十步出锅食用的是什么”它答不对。它可能说“五花肉”,但实际上应该是“红烧肉”。生的是五花肉,做熟了是红烧肉。

是红烧五花肉呀。一定要说红烧熟了的五花肉吗?

孺子可教。其实不能怪它缺乏常识,要怪就怪中文,cooked 与 cooking 全不分。“红烧肉”实际上既是名词(定中结构)也是动词短语(动宾结构),到哪里说理去。

宋柔:如果有食谱知识,应该说红烧肉,五花肉是材料,红烧是做法,成品是红烧肉。“面粉1斤,加水和好,发酵搓揉后切成5段,切成长方块,放入笼屉中,大火蒸30分钟,掀开笼屉便可吃了”。请问可吃的是什么?

宋柔:不容易。确实有常识了。但是仅凭长方块而排除包子显然不大正确。包子一定有馅,但制作过程没加馅。

总之,除了缺了口热乎气儿,它就是个人,是个会犯懒,也会犯错误的人。

【原则1技巧4】可以用 few shots 示例。

所谓 few-shot prompting,基本上就是用案例让模型知道要做什么,要求照葫芦画瓢。例如:

曾几何时,还在 GPT3 刚放出来的时候,圈子内的粉丝们都到它的 playground 去玩,当时的主要技巧就是 few shots,因为 ChatGPT 之前,zero shot 的能力还没成熟。等到 ChatGPT 能直接听懂人的指令,zero shot 很好使,用户自然而然就不再使用啰嗦的 few shots。但实际上,并不影响你继续使用 few shots,或与 zero shot 一起用。在有些不大容易说清楚的任务上,拿 few shots 补充 zero shot 可以加强效果。

【原则2: 让模型有时间“思考”】

【原则2技巧1】为复杂的任务列出步骤。

这项技巧的原文这样要求:“specify the steps required to complete a task.” 

上述提示词遵循了 best practice:1. 用了分隔符三个反引号;2. 任务分解为一系列步骤或子任务;3. 对输出提出了格式化要求。

感觉这就是在编程序,是自然语言的低代码形式,自然语言让人人可以成为程序猿,指挥机器做我们想要它做的事儿。

【原则2技巧2】要求模型独立解题。

看上去就是以前说的 step by step (思维链)解题指令,原文说得更像个对于辅导员的要求:“Our next tactic is to instruct the model to work out its own solution before rushing to a conclusion.” 尤其是在智能教育场景,希望模型先独立一步一步做题,然后再去充当老师给学生评判作业。

所示范的案例是评阅数学问题。有一个数学问题,也有学生的解答。

Determine if the student's solution is correct or not.

Question:
I'm building a solar power installation and I need help working out the financials. 
- Land costs $100 / square foot
- I can buy solar panels for $250 / square foot
- I negotiated a contract for maintenance that will cost me a flat $100k per year, and an additional $10 / square foot
What is the total cost for the first year of operations as a function of the number of square feet.

Student's Solution:
Let x be the size of the installation in square feet.
Costs:
1. Land cost: 100x
2. Solar panel cost: 250x
3. Maintenance cost: 100,000 + 100x
Total cost: 100x + 250x + 100,000 + 100x = 450x + 100,000

学生的解答实际上是错误的,因为他们将维护成本计算为10万美元加上100x,但实际上应该是10x,因为每平方英尺只要10美元($10 / square foot),其中x是安装面积的大小,按平方英尺算。所以这实际上应该是360x加上10万美元。让模型评判,它会说学生的解答是正确的。模型只是浏览了一下,就同意了学生的看法。可以通过指示模型先自己解决问题并将其解决方案与学生的解决方案进行比较来解决这个问题。看提示词是怎么指示的:

prompt = f"""
Your task is to determine if the student's solution is correct or not.
To solve the problem do the following:
- First, work out your own solution to the problem. 
- Then compare your solution to the student's solution and evaluate if the student's solution is correct or not. Don't decide if the student's solution is correct until you have done the problem yourself.

Use the following format:
Question:
```
question here
```
Student's solution:
```
student's solution here
```
Actual solution:
```
steps to work out the solution and your solution here
```
Is the student's solution the same as actual solution just calculated:
```
yes or no
```
Student grade:
```
correct or incorrect
```

Actual solution:
"""

这个提示很长。因此,我们在这个提示中告诉模型要做什么。你的任务是确定学生的解决方案是否正确。为了解决这个问题,请执行以下操作。首先,解决问题。然后将你的解决方案与学生的解决方案进行比较,并评估学生的解决方案是否正确。在你自己做完问题之前不要决定学生的解决方案是否正确。确保你自己做了这个问题。因此,我们已经使用了相同的技巧来使用以下格式。因此,格式将是问题、学生的解决方案、实际的解决方案。然后是解决方案是否一致,是或否。然后是学生的成绩,正确或不正确。

如你所见,模型实际上会先计算出自己的答案。然后,它得到了正确的答案。然后,在被要求与学生的解决方案进行比较时,它意识到它们不一致。因此,学生实际上是不正确的。这是一个例子,说明学生的解决方案是正确的,而实际上学生的解决方案是错误的。这是如何要求模型自己进行计算,并将任务分解为步骤以给模型更多时间来思考,从而帮助您获得更准确的响应的示例。

 

 

 

 

AI浪潮博客目录

Andrew Ng: 提示工程的课程